LOCUS       SIU00441.1               409 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 ppe
            family protein ppe32 protein.
ACCESSION   LT708304-1854
PROTEIN_ID  SIU00441.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PPE32"
                     /locus_tag="BQ2027_MB1837"
                     /note="Mb1837, PPE32, len: 409 aa. Equivalent to Rv1808,
                     len: 409 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.000% identity in 409 aa overlap). Member of the
                     Mycobacterium tuberculosis PPE family of glycine-rich
                     proteins, most similar to Rv1800|MTV049.22|AL022021 (655
                     aa), FASTA scores: opt: 1225, E(): 0, (55.1% identity in
                     423 aa overlap). Contains PS00343 Gram-positive cocci
                     surface proteins 'anchoring' hexapeptide. TBparse score is
                     0.919. Protein product from Mb1837 detected using shotgun
                     mass spectrometry and SWATH mass spectrometry. Mb1837
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR000030"
                     /db_xref="InterPro:IPR022171"
                     /db_xref="InterPro:IPR038332"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZC6"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MDFGALPPEI NSGRMYAGPG SGPLLAAAAA WDALAAELYS AAASYGSTIE GLTVAPWMGP
       61 SSITMAAAVA PYVAWISVTA GQAEQAGAQA KIAAGVYETA FAATVPPPVI EANRALLMSL
      121 VATNIFGQNT PAIAATEAHY AEMWAQDAAA MYGYAGSSAT ASQLAPFSEP PQTTNPSATA
      181 AQSAVVAQAA GAAASSDITA QLSQLISLLP STLQSLATTA TATSASAGWD TVLQSITTIL
      241 ANLTGPYSII GLGAIPGGWW LTFGQILGLA QNAPGVAALL GPKAAAGALS PLAPLRGGYI
      301 ADITPLGGGA TGGIARAIYV GSLSVPQGWA EAAPVMRAVA SVLPGTGAAP ALAAEAPGAL
      361 FGEMALSSLA GRALAGTAVR SGAGAARVAG GSVTEDVAST TTIIVIPAD
//