LOCUS       SIU00432.1               655 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 ppe
            family protein ppe28 protein.
ACCESSION   LT708304-1845
PROTEIN_ID  SIU00432.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PPE28"
                     /locus_tag="BQ2027_MB1828"
                     /note="Mb1828, PPE28, len: 655 aa. Equivalent to Rv1800,
                     len: 655 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.5% identity in 655 aa overlap). Member of the
                     Mycobacterium tuberculosis PPE family of glycine-rich
                     proteins, C-terminal very similar to parts of PE proteins
                     e.g. Z92770|MTCI5.25|Rv0151c (588 aa), FASTA scores: opt:
                     1269, E(): 0, (41.5% identity in 591 aa overlap). Mb1828
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR000030"
                     /db_xref="InterPro:IPR013228"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="InterPro:IPR038332"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZC0"
BEGIN
        1 MLPNFAVLPP EVNSARVFAG AGSAPMLAAA AAWDDLASEL HCAAMSFGSV TSGLVVGWWQ
       61 GSASAAMVDA AASYIGWLST SAAHAEGAAG LARAAVSVFE EALAATVHPA MVAANRAQVA
      121 SLVASNLFGQ NAPAIAALES LYEWMWAQDA AAMAGYYVGA SAVATQLASW LQRLQSIPGA
      181 ASLDARLPSS AEAPMGVVRA VNSAIAANAA AAQTVGLVMG GSGTPIPSAR YVELANALYM
      241 SGSVPGVIAQ ALVTPQGLYP VVVIKNLTFD SSVAQGAVIL ESAIRQQIAA GNNVTVFGYS
      301 QSATISSLVM ANLAASADPP SPDELSFTLI GNPNNPNGGV ATRFPGISFP SLGVTATGAT
      361 PHNLYPTKIY TIEYDGVADF PRYPLNFVST LNAIAGTYYV HSNYFILTPE QIDAAVPLTN
      421 TVGPTMTQYY IIRTENLPLL EPLRSVPIVG NPLANLVQPN LKVIVNLGYG DPAYGYSTSP
      481 PNVATPFGLF PEVSPVVIAD ALAAGTQQGI GDFAYDVSHL ELPLPADGST MPSTAPGSGT
      541 PVPPLSIDSL IDDLQVANRN LANTISKVAA TSYATVLPTA DIANAALTIV PSYNIHLFLE
      601 GIQQALKGDP MGLVNAVGYP LAADVALFTA AGGLQLLIII SAGRTIANDI SAIVP
//