LOCUS SIU00432.1 655 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 ppe family protein ppe28 protein. ACCESSION LT708304-1845 PROTEIN_ID SIU00432.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="PPE28" /locus_tag="BQ2027_MB1828" /note="Mb1828, PPE28, len: 655 aa. Equivalent to Rv1800, len: 655 aa, from Mycobacterium tuberculosis strain H37Rv, (99.5% identity in 655 aa overlap). Member of the Mycobacterium tuberculosis PPE family of glycine-rich proteins, C-terminal very similar to parts of PE proteins e.g. Z92770|MTCI5.25|Rv0151c (588 aa), FASTA scores: opt: 1269, E(): 0, (41.5% identity in 591 aa overlap). Mb1828 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR000030" /db_xref="InterPro:IPR013228" /db_xref="InterPro:IPR029058" /db_xref="InterPro:IPR038332" /db_xref="UniProtKB/TrEMBL:A0A1R3XZC0" BEGIN 1 MLPNFAVLPP EVNSARVFAG AGSAPMLAAA AAWDDLASEL HCAAMSFGSV TSGLVVGWWQ 61 GSASAAMVDA AASYIGWLST SAAHAEGAAG LARAAVSVFE EALAATVHPA MVAANRAQVA 121 SLVASNLFGQ NAPAIAALES LYEWMWAQDA AAMAGYYVGA SAVATQLASW LQRLQSIPGA 181 ASLDARLPSS AEAPMGVVRA VNSAIAANAA AAQTVGLVMG GSGTPIPSAR YVELANALYM 241 SGSVPGVIAQ ALVTPQGLYP VVVIKNLTFD SSVAQGAVIL ESAIRQQIAA GNNVTVFGYS 301 QSATISSLVM ANLAASADPP SPDELSFTLI GNPNNPNGGV ATRFPGISFP SLGVTATGAT 361 PHNLYPTKIY TIEYDGVADF PRYPLNFVST LNAIAGTYYV HSNYFILTPE QIDAAVPLTN 421 TVGPTMTQYY IIRTENLPLL EPLRSVPIVG NPLANLVQPN LKVIVNLGYG DPAYGYSTSP 481 PNVATPFGLF PEVSPVVIAD ALAAGTQQGI GDFAYDVSHL ELPLPADGST MPSTAPGSGT 541 PVPPLSIDSL IDDLQVANRN LANTISKVAA TSYATVLPTA DIANAALTIV PSYNIHLFLE 601 GIQQALKGDP MGLVNAVGYP LAADVALFTA AGGLQLLIII SAGRTIANDI SAIVP //