LOCUS SIU00429.1 406 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 esx conserved component ecce5. esx-5 type vii secretion system protein. probable membrane protein. protein. ACCESSION LT708304-1842 PROTEIN_ID SIU00429.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="ecce5" /locus_tag="BQ2027_MB1825" /note="Mb1825, -, len: 406 aa. Equivalent to Rv1797, len: 406 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 406 aa overlap). Conserved hypothetical protein, some similarity to Mycobacterium tuberculosis O05462|Rv3882c|MTCY15F10.30|Z94121 (462 aa), FASTA scores: opt: 181, E(): 9.2e-05, (25.4% identity in 283 aa overlap). Has hydrophobic stretch near N-terminus. Protein product from Mb1825 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1825 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XZD1" /db_xref="InterPro:IPR021368" /db_xref="UniProtKB/TrEMBL:A0A1R3XZD1" BEGIN 1 MKAQRSFGLA LSWPRVTAVF LVDVLILAVA SHCPDSWQAD HHVAWWVGVG VAAVVTLLSV 61 VSYHGITVIS GLATWVRDWS ADPGTTLGAG CTPAIDHQRR FGRDTVGVRE YNGRLVSVIE 121 VTCGESGPSG RHWHRKSPVP MLPVVAVADG LRQFDIHLDG IDIVSVLVRG GVDAAKASAS 181 LQEWEPQGWK SEERAGDRTV ADRRRTWLVL RMNPQRNVAA VACRDSLAST LVAATERLVQ 241 DLDGQSCAAR PVTADELTEV DSAVLADLEP TWSRPGWRHL KHFNGYATSF WVTPSDITSE 301 TLDELCLPDS PEVGTTVVTV RLTTRVGSPA LSAWVRYHSD TRLPKEVAAG LNRLTGRQLA 361 AVRASLPAPT HRPLLVIPSR NLRDHDELVL PVGQELEHAT SSFVGQ //