LOCUS       SIU00429.1               406 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 esx
            conserved component ecce5. esx-5 type vii secretion system
            protein. probable membrane protein. protein.
ACCESSION   LT708304-1842
PROTEIN_ID  SIU00429.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="ecce5"
                     /locus_tag="BQ2027_MB1825"
                     /note="Mb1825, -, len: 406 aa. Equivalent to Rv1797, len:
                     406 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 406 aa overlap). Conserved
                     hypothetical protein, some similarity to Mycobacterium
                     tuberculosis O05462|Rv3882c|MTCY15F10.30|Z94121 (462 aa),
                     FASTA scores: opt: 181, E(): 9.2e-05, (25.4% identity in
                     283 aa overlap). Has hydrophobic stretch near N-terminus.
                     Protein product from Mb1825 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1825 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XZD1"
                     /db_xref="InterPro:IPR021368"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZD1"
BEGIN
        1 MKAQRSFGLA LSWPRVTAVF LVDVLILAVA SHCPDSWQAD HHVAWWVGVG VAAVVTLLSV
       61 VSYHGITVIS GLATWVRDWS ADPGTTLGAG CTPAIDHQRR FGRDTVGVRE YNGRLVSVIE
      121 VTCGESGPSG RHWHRKSPVP MLPVVAVADG LRQFDIHLDG IDIVSVLVRG GVDAAKASAS
      181 LQEWEPQGWK SEERAGDRTV ADRRRTWLVL RMNPQRNVAA VACRDSLAST LVAATERLVQ
      241 DLDGQSCAAR PVTADELTEV DSAVLADLEP TWSRPGWRHL KHFNGYATSF WVTPSDITSE
      301 TLDELCLPDS PEVGTTVVTV RLTTRVGSPA LSAWVRYHSD TRLPKEVAAG LNRLTGRQLA
      361 AVRASLPAPT HRPLLVIPSR NLRDHDELVL PVGQELEHAT SSFVGQ
//