LOCUS SIU00414.1 724 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE 4-ALPHA-GLUCANOTRANSFERASE MALQ (Amylomaltase) (Disproportionating enzyme) (D-enzyme) protein. ACCESSION LT708304-1827 PROTEIN_ID SIU00414.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="malQ" /locus_tag="BQ2027_MB1810C" /note="Mb1810c, malQ, len: 724 aa. Equivalent to Rv1781c, len: 724 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 724 aa overlap). Probable malQ, 4-ALPHA-GLUCANOTRANSFERASE (EC 2.4.1.25), similar to many, e.g. P15977|MALQ_ECOLI 4-ALPHA-GLUCANOTRANSFERASE (694 aa), FASTA scores: opt: 964, E(): 0, (31.8% identity in 694 aa overlap). BELONGS TO THE DISPROPORTIONATING ENZYME FAMILY. Protein product from Mb1810c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1810c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P65337" /db_xref="InterPro:IPR003385" /db_xref="InterPro:IPR017853" /db_xref="UniProtKB/Swiss-Prot:P65337" BEGIN 1 MTELAPSLVE LARRFGIATE YTDWTGRQVL VSEATLVAAL AALGVPAQTE QQRNDALAAQ 61 LRSYWARPLP ATIVMRAGEQ TQFRVHVTDG APADVWLQLE DGTTRAEVVQ VDNFTPPFDL 121 DGRWIGEASF VLPADLPLGY HRVNLRSGDS QASAAVVVTP DWLGLPDKLA GRRAWGLAVQ 181 LYSVRSRQSW GIGDLTDLAN LALWSASAHG AGYVLVNPLH AATLPGPAGR SKPIEPSPYL 241 PTSRRFVNPL YLRVEAIPEL VDLPKRGRVQ RLRTNVQQHA DQLDTIDRDS AWAAKRAALK 301 LVHRVPRSAG RELAYAAFRT REGRALDDFA TWCALAETYG DDWHRWPKSL RHPDASGVAD 361 FVDKHADAVD FHRWLQWQLD EQLASAQSQA LRAGMSLGIM ADLAVGVHPN GADAWALQDV 421 LAQGVTAGAP PDEFNQLGQD WSQPPWRPDR LAEQEYRPFR ALIQAALRHA GAVRIDHIIG 481 LFRLWWIPDG APPTQGTYVR YDHDAMIGIV ALEAHRAGAV VVGEDLGTVE PWVRDYLLLR 541 GLLGTSILWF EQDRDCGPAG TPLPAERWRE YCLSSVTTHD LPPTAGYLAG DQVRLRESLG 601 LLTNPVEAEL ESARADRAAW MAELRRVGLL ADGAEPDSEE AVLALYRYLG RTPSRLLAVA 661 LTDAVGDRRT QNQPGTTDEY PNWRVPLTGP DGQPMLLEDI FTDRRAATLA EAVRAATTSP 721 MSCW //