LOCUS SIU00409.1 186 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN protein. ACCESSION LT708304-1822 PROTEIN_ID SIU00409.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1805C" /note="Mb1805c, -, len: 186 aa. Equivalent to Rv1776c, len: 186 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 186 aa overlap). Possible regulatory protein, some similarity to Mycobacterium tuberculosis Rv1255c|Q11063 hypothetical transcriptional regulator (202 aa), FASTA scores: opt: 270, E(): 9.7e-09, (28.3% identity in 191 aa overlap) . Contains possible helix-turn-helix motif at aa 37-58 (+3.49 SD). Mb1805c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:A0A1R3XZB2" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="UniProtKB/TrEMBL:A0A1R3XZB2" BEGIN 1 MPGNDWIVGG NRRTIAAERI YAAATDLITR YGLNALDIDK LAREVHCSRA TIYRRAGGKA 61 QIRDVVLTRA AARIADGVRS DVETLRGRER VVAAILLSLQ RIRSDPLGKL MFGSIHGGAG 121 ELAWLTESPL LADFATELTG IAGGDPQGAK WVVRVVLSLM YWPAENDEAE RRLVEKYVAP 181 AFAEQS //