LOCUS       SIU00409.1               186 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            TRANSCRIPTIONAL REGULATORY PROTEIN protein.
ACCESSION   LT708304-1822
PROTEIN_ID  SIU00409.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1805C"
                     /note="Mb1805c, -, len: 186 aa. Equivalent to Rv1776c,
                     len: 186 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 186 aa overlap). Possible regulatory
                     protein, some similarity to Mycobacterium tuberculosis
                     Rv1255c|Q11063 hypothetical transcriptional regulator (202
                     aa), FASTA scores: opt: 270, E(): 9.7e-09, (28.3% identity
                     in 191 aa overlap) . Contains possible helix-turn-helix
                     motif at aa 37-58 (+3.49 SD). Mb1805c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3XZB2"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZB2"
BEGIN
        1 MPGNDWIVGG NRRTIAAERI YAAATDLITR YGLNALDIDK LAREVHCSRA TIYRRAGGKA
       61 QIRDVVLTRA AARIADGVRS DVETLRGRER VVAAILLSLQ RIRSDPLGKL MFGSIHGGAG
      121 ELAWLTESPL LADFATELTG IAGGDPQGAK WVVRVVLSLM YWPAENDEAE RRLVEKYVAP
      181 AFAEQS
//