LOCUS SIU00369.1 395 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE NITRATE/NITRITE TRANSPORTER NARK2 protein. ACCESSION LT708304-1782 PROTEIN_ID SIU00369.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="narK2" /locus_tag="BQ2027_MB1766C" /note="Mb1766c, narK2, len: 395 aa. Equivalent to Rv1737c, len: 395 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 395 aa overlap). Possible narK2, nitrate/nitrite-transport integral membrane protein (see first citation below), possibly member of major facilitator superfamily (MFS), similar to P46907|NARK_BACSU nitrite extrusion protein from Bacillus subtilis (395 aa), FASTA scores: opt: 742, E(): 0, (33.6% identity in 375 aa overlap); and to AL109989|SCJ12.23 hypothetical nitrate/nitrite transporter from Streptomyces coelicolor (412 aa), FASTA scores: opt: 1181, E(): 0, (49.4% identity in 389 aa overlap). Protein product from Mb1766c detected using SWATH mass spectrometry." /db_xref="GOA:A0A1R3XZ73" /db_xref="InterPro:IPR011701" /db_xref="InterPro:IPR020846" /db_xref="InterPro:IPR036259" /db_xref="UniProtKB/TrEMBL:A0A1R3XZ73" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MRGQAANLVL ATWISVVNFW AWNLIGPLST SYARDMSLSS AEASLLVATP ILVGALGRIV 61 TGPLTDRFGG RAMLIAVTLA SILPVLAVGV AATMGSYALL VFFGLFLGVA GTIFAVGIPF 121 ANNWYQPARR GFSTGVFGMG MVGTALSAFF TPRFVRWFGL FTTHAIVAAA LASTAVVAMV 181 VLRDAPYFRP NADPVLPRLK AAARLPVTWE MSFLYAIVFG GFVAFSNYLP TYITTIYGFS 241 TVDAGARTAG FALAAVLARP VGGWLSDRIA PRHVVLASLA GTALLAFAAA LQPPPEVWSA 301 ATFITLAVCL GVGTGGVFAW VARRAPAASV GSVTGIVAAA GGLGGYFPPL VMGATYDPVD 361 NDYTVGLLLL VATALVACTY TALHAREPVS EEASR //