LOCUS       SIU00354.1               494 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            CARBOXYLASE protein.
ACCESSION   LT708304-1767
PROTEIN_ID  SIU00354.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1751"
                     /note="Mb1751, -, len: 494 aa. Equivalent to Rv1722, len:
                     494 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.8% identity in 494 aa overlap). Possible carboxylases.
                     Weak similarity to several e.g. ACCC_BACSU|P49787 biotin
                     carboxylase from Bacillus subtilis (448 aa), fasta scores:
                     opt: 171, E(): 0.00021, (22.8% identity in 237 aa
                     overlap). Protein product from Mb1751 detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb1751 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XZY7"
                     /db_xref="InterPro:IPR011761"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZY7"
BEGIN
        1 MIVPAREPEP QPRRVLNGLS DVRAFFHNNT MPLYFISPTP FNLLGIYRWI RNFFYLTYYD
       61 SFEGEHSRVF VPRRRDRRDF DGMGDVCNHL LRDPETLEFI KNRGPGGKAC FVMLDEETQA
      121 LARQAGLEVM HPPAELRHRL ESKIVMTRLA DEAGVPSVPH VIGRVSSYDE LSALAHGAGL
      181 GDDLVVEAAY GNAGSATFFV RGLRDWDQCA GGIVGQPEIK VMKRIRNVEV CIEATVTRHG
      241 TVIGPAMTSL VGYPELTPYR GAWCGNDVWR GALPPAQTRA AREMVAKLGD VLSREGYRGY
      301 FEVDLLHDLD ADELYLGEVN PRLSGASPMT NLTTEAYADM PLFLFHLLEY MDVDYELDIE
      361 AINSRWERGY GEDEVWGQLI MSETSPDLEL FTATPRTGMW RLNHDGRVSF ARQGNDWATM
      421 LDESEAFYMR VAAPGDLRCE GAQLGVLVTR GHLQTDDYQL TERGRRWIDG LKAQFASTPL
      481 TPAAPIVSRL VARA
//