LOCUS SIU00354.1 494 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE CARBOXYLASE protein. ACCESSION LT708304-1767 PROTEIN_ID SIU00354.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1751" /note="Mb1751, -, len: 494 aa. Equivalent to Rv1722, len: 494 aa, from Mycobacterium tuberculosis strain H37Rv, (99.8% identity in 494 aa overlap). Possible carboxylases. Weak similarity to several e.g. ACCC_BACSU|P49787 biotin carboxylase from Bacillus subtilis (448 aa), fasta scores: opt: 171, E(): 0.00021, (22.8% identity in 237 aa overlap). Protein product from Mb1751 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1751 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XZY7" /db_xref="InterPro:IPR011761" /db_xref="UniProtKB/TrEMBL:A0A1R3XZY7" BEGIN 1 MIVPAREPEP QPRRVLNGLS DVRAFFHNNT MPLYFISPTP FNLLGIYRWI RNFFYLTYYD 61 SFEGEHSRVF VPRRRDRRDF DGMGDVCNHL LRDPETLEFI KNRGPGGKAC FVMLDEETQA 121 LARQAGLEVM HPPAELRHRL ESKIVMTRLA DEAGVPSVPH VIGRVSSYDE LSALAHGAGL 181 GDDLVVEAAY GNAGSATFFV RGLRDWDQCA GGIVGQPEIK VMKRIRNVEV CIEATVTRHG 241 TVIGPAMTSL VGYPELTPYR GAWCGNDVWR GALPPAQTRA AREMVAKLGD VLSREGYRGY 301 FEVDLLHDLD ADELYLGEVN PRLSGASPMT NLTTEAYADM PLFLFHLLEY MDVDYELDIE 361 AINSRWERGY GEDEVWGQLI MSETSPDLEL FTATPRTGMW RLNHDGRVSF ARQGNDWATM 421 LDESEAFYMR VAAPGDLRCE GAQLGVLVTR GHLQTDDYQL TERGRRWIDG LKAQFASTPL 481 TPAAPIVSRL VARA //