LOCUS       SIU00352.1               129 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            toxin vapc12 protein.
ACCESSION   LT708304-1765
PROTEIN_ID  SIU00352.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="vapc12"
                     /locus_tag="BQ2027_MB1749C"
                     /note="Mb1749c, -, len: 129 aa. Equivalent to Rv1720c,
                     len: 129 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 129 aa overlap). Conserved hypothetical
                     protein, similar to other Mycobacterium tuberculosis
                     hypothetical proteins e.g. O53610|Rv0065|MTV030.08 (133
                     aa), FASTA scores: E(): 1.5e-10, (39.1% identity in 128 aa
                     overlap); P71550|Rv0960|MTCY10D7.14C (129 aa) and
                     O06415|Rv0549c|MTCY25D10.28C (137 aa). Mb1749c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XZ41"
                     /db_xref="InterPro:IPR002716"
                     /db_xref="InterPro:IPR022907"
                     /db_xref="InterPro:IPR029060"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZ41"
BEGIN
        1 MIVLDASAAV ELMLTTPAGA AVARRLRGET VHAPAHFDVE VIGAIRQAVV RQLISDHEGL
       61 VVVVNFLSLP VRRWPLKPFT QRAYQLRSTH TVADGAYVAL AEGLGVPLIT CDGRLAQSHG
      121 HNAEIELVA
//