LOCUS SIU00351.1 259 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN protein. ACCESSION LT708304-1764 PROTEIN_ID SIU00351.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1748" /note="Mb1748, -, len: 259 aa. Equivalent to Rv1719, len: 259 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 259 aa overlap). Probable transcriptional regulatory protein, similar to YIAJ_ECOLI|P37671 hypothetical transcriptional regulator from Escherichia coli (282 aa), FASTA scores: opt: 353, E(): 3.2e-15, (31.1% identity in 235 aa overlap). Similar to Mycobacterium tuberculosis hypothetical IclR-family transcriptional regulators Rv2989, Rv1773c. Helix-turn-helix motif from aa 34-55 (+6.94 SD). Protein product from Mb1748 detected using shotgun mass spectrometry and SWATH mass spectrometry." /db_xref="GOA:A0A1R3XZ29" /db_xref="InterPro:IPR005471" /db_xref="InterPro:IPR012318" /db_xref="InterPro:IPR014757" /db_xref="InterPro:IPR029016" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="UniProtKB/TrEMBL:A0A1R3XZ29" BEGIN 1 MSAEEQDTRS GGIQVIARAA ELLRVLQAHP GGLSQAEIGE RVGMARSTVS RILNALEDEG 61 LVASRGARGP YRLGPEITRM ATTVRLGVVT EMHPFLTELS RELDETVDLS ILDGDRADVV 121 DQVVPPQRLR AVSAVGESFP LYCCANGKAL LAALPPERQA RALPSRLAPL TANTITDRAA 181 LRDELNRIRV DGVAYDREEQ TEGICAVGAV LRGVSVELVA VSVPVPAQRF YGREAELAGA 241 LLAWVSKVDA WFNGTEDRK //