LOCUS       SIU00351.1               259 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            TRANSCRIPTIONAL REGULATORY PROTEIN protein.
ACCESSION   LT708304-1764
PROTEIN_ID  SIU00351.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1748"
                     /note="Mb1748, -, len: 259 aa. Equivalent to Rv1719, len:
                     259 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 259 aa overlap). Probable
                     transcriptional regulatory protein, similar to
                     YIAJ_ECOLI|P37671 hypothetical transcriptional regulator
                     from Escherichia coli (282 aa), FASTA scores: opt: 353,
                     E(): 3.2e-15, (31.1% identity in 235 aa overlap). Similar
                     to Mycobacterium tuberculosis hypothetical IclR-family
                     transcriptional regulators Rv2989, Rv1773c.
                     Helix-turn-helix motif from aa 34-55 (+6.94 SD). Protein
                     product from Mb1748 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry."
                     /db_xref="GOA:A0A1R3XZ29"
                     /db_xref="InterPro:IPR005471"
                     /db_xref="InterPro:IPR012318"
                     /db_xref="InterPro:IPR014757"
                     /db_xref="InterPro:IPR029016"
                     /db_xref="InterPro:IPR036388"
                     /db_xref="InterPro:IPR036390"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZ29"
BEGIN
        1 MSAEEQDTRS GGIQVIARAA ELLRVLQAHP GGLSQAEIGE RVGMARSTVS RILNALEDEG
       61 LVASRGARGP YRLGPEITRM ATTVRLGVVT EMHPFLTELS RELDETVDLS ILDGDRADVV
      121 DQVVPPQRLR AVSAVGESFP LYCCANGKAL LAALPPERQA RALPSRLAPL TANTITDRAA
      181 LRDELNRIRV DGVAYDREEQ TEGICAVGAV LRGVSVELVA VSVPVPAQRF YGREAELAGA
      241 LLAWVSKVDA WFNGTEDRK
//