LOCUS SIU00345.1 270 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable oxidoreductase protein. ACCESSION LT708304-1758 PROTEIN_ID SIU00345.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1741" /note="Mb1741, -, len: 270 aa. Equivalent to Rv1714, len: 270 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 270 aa overlap). Probable oxidoreductase (EC 1.-.-.-) similar to many e.g. AE0010|AE001021_4 Archaeoglobus fulgidus section 79 (281 aa), FASTA scores: opt: 578, E(): 3.3e-31, (38.9% identity in 265 aa overlap). Also similar to several other Mycobacterium tuberculosis oxidoreductases e.g. Rv1544, etc. Mb1741 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR036291" /db_xref="UniProtKB/TrEMBL:A0A1R3XZ44" BEGIN 1 MEEMALAQQV PNLGLARFSV QDKSILITGA TGSLGRVAAR ALADAGARLT LAGGNSAGLA 61 ELVNGAGIDD AAVVTCRPDS LADAQQMVEA ALGRYGRLDG VLVASGSNHV APITEMAVED 121 FDAVMDANVR GAWLVCRAAG RVLLEQGQGG SVVLVSSVRG GLGNAAGYSA YCPSKAGTDL 181 LAKTLAAEWG GHGIRVNALA PTVFRSAVTE WMFTDDPKGR ATREAMLARI PLRRFAEPED 241 FVGALIYLLS DASSFYTGQV MYLDGGYTAC //