LOCUS       SIU00345.1               270 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            oxidoreductase protein.
ACCESSION   LT708304-1758
PROTEIN_ID  SIU00345.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1741"
                     /note="Mb1741, -, len: 270 aa. Equivalent to Rv1714, len:
                     270 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 270 aa overlap). Probable oxidoreductase
                     (EC 1.-.-.-) similar to many e.g. AE0010|AE001021_4
                     Archaeoglobus fulgidus section 79 (281 aa), FASTA scores:
                     opt: 578, E(): 3.3e-31, (38.9% identity in 265 aa
                     overlap). Also similar to several other Mycobacterium
                     tuberculosis oxidoreductases e.g. Rv1544, etc. Mb1741
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZ44"
BEGIN
        1 MEEMALAQQV PNLGLARFSV QDKSILITGA TGSLGRVAAR ALADAGARLT LAGGNSAGLA
       61 ELVNGAGIDD AAVVTCRPDS LADAQQMVEA ALGRYGRLDG VLVASGSNHV APITEMAVED
      121 FDAVMDANVR GAWLVCRAAG RVLLEQGQGG SVVLVSSVRG GLGNAAGYSA YCPSKAGTDL
      181 LAKTLAAEWG GHGIRVNALA PTVFRSAVTE WMFTDDPKGR ATREAMLARI PLRRFAEPED
      241 FVGALIYLLS DASSFYTGQV MYLDGGYTAC
//