LOCUS       SIU00342.1               254 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 LSU
            rRNA pseudouridine(2605) synthase (EC protein.
ACCESSION   LT708304-1755
PROTEIN_ID  SIU00342.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1738"
                     /EC_number="5.4.99.22"
                     /note="Mb1738, -, len: 254 aa. Equivalent to Rv1711, len:
                     254 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 254 aa overlap). Conserved hypothetical
                     protein, highly similar to a large family of hypothetical
                     proteins e.g. P37765|YCIL_ECOLI from Escherichia coli (291
                     aa), FASTA scores: opt: 496, E(): 1.1e-29, (41.6% identity
                     in 250 aa overlap); 9S232|SCI51.08C|AL109848 PUTATIVE
                     PSEUDOURIDINE SYNTHASE from Streptomyces coelicolor (371
                     aa), FASTA scores: opt: 818, E(): 0, (53.1% identity in
                     245 aa overlap). Equivalent to O05668|MLCB1351.03C|Z95117
                     Hypothetical protein from Mycobacterium leprae (256 aa),
                     (80.5% identity in 256 aa overlap). Contains PS01149
                     Hypothetical yciL/yejD/yjbC family signature. Protein
                     product from Mb1738 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1738 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P65843"
                     /db_xref="InterPro:IPR000748"
                     /db_xref="InterPro:IPR002942"
                     /db_xref="InterPro:IPR006145"
                     /db_xref="InterPro:IPR018496"
                     /db_xref="InterPro:IPR020103"
                     /db_xref="InterPro:IPR036986"
                     /db_xref="InterPro:IPR042092"
                     /db_xref="UniProtKB/Swiss-Prot:P65843"
BEGIN
        1 MMAEPEESRE PRGIRLQKVL SQAGIASRRA AEKMIVDGRV EVDGHVVTEL GTRVDPQVAV
       61 VRVDGARVVL DDSLVYLALN KPRGMHSTMS DDRGRPCIGD LIERKVRGTK KLFHVGRLDA
      121 DTEGLMLLTN DGELAHRLMH PSHEVPKTYL ATVTGSVPRG LGRTLRAGIE LDDGPAFVDD
      181 FAVVDAIPGK TLVRVTLHEG RNRIVRRLLA AAGFPVEALV RTDIGAVSLG KQRPGSVRAL
      241 RSNEIGQLYQ AVGL
//