LOCUS       SIU00336.1               394 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 ppe
            family protein ppe23 protein.
ACCESSION   LT708304-1749
PROTEIN_ID  SIU00336.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PPE23"
                     /locus_tag="BQ2027_MB1732C"
                     /note="Mb1732c, PPE23, len: 394 aa. Equivalent to Rv1706c,
                     len: 394 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 394 aa overlap). Member of the M.
                     tuberculosis PPE family of glycine-rich proteins, similar
                     to many e.g. YX23_MYCTU|Q10813 hypothetical 41.1 kd
                     protein cy274.23 (404 aa), fasta scores: opt: 841, E():
                     3.9e-31, (46.8% identity in 408 aa overlap). Mb1732c found
                     to be expressed during exponential growth in Sauton's
                     minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR000030"
                     /db_xref="InterPro:IPR022171"
                     /db_xref="InterPro:IPR038332"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZG1"
BEGIN
        1 MTLDVPVNQG HVPPGSVACC LVGVTAVADG IAGHSLSNFG ALPPEINSGR MYSGPGSGPL
       61 MAAAAAWDGL AAELSSAATG YGAAISELTN MRWWSGPASD SMVAAVLPFV GWLSTTATLA
      121 EQAAMQARAA AAAFEAAFAM TVPPPAIAAN RTLLMTLVDT NWFGQNTPAI ATTESQYAEM
      181 WAQDAAAMYG YASAAAPATV LTPFAPPPQT TNATGLVGHA TAVAALRGQH SWAAAIPWSD
      241 IQKYWMMFLG ALATAEGFIY DSGGLTLNAL QFVGGMLWST ALAEAGAAEA AAGAGGAAGW
      301 SAWSQLGAGP VAASATLAAK IGPMSVPPGW SAPPATPQAQ TVARSIPGIR SAAEAAETSV
      361 LLRGAPTPGR SRAAHMGRRY GRRLTVMADR PNVG
//