LOCUS SIU00336.1 394 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 ppe family protein ppe23 protein. ACCESSION LT708304-1749 PROTEIN_ID SIU00336.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="PPE23" /locus_tag="BQ2027_MB1732C" /note="Mb1732c, PPE23, len: 394 aa. Equivalent to Rv1706c, len: 394 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 394 aa overlap). Member of the M. tuberculosis PPE family of glycine-rich proteins, similar to many e.g. YX23_MYCTU|Q10813 hypothetical 41.1 kd protein cy274.23 (404 aa), fasta scores: opt: 841, E(): 3.9e-31, (46.8% identity in 408 aa overlap). Mb1732c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR000030" /db_xref="InterPro:IPR022171" /db_xref="InterPro:IPR038332" /db_xref="UniProtKB/TrEMBL:A0A1R3XZG1" BEGIN 1 MTLDVPVNQG HVPPGSVACC LVGVTAVADG IAGHSLSNFG ALPPEINSGR MYSGPGSGPL 61 MAAAAAWDGL AAELSSAATG YGAAISELTN MRWWSGPASD SMVAAVLPFV GWLSTTATLA 121 EQAAMQARAA AAAFEAAFAM TVPPPAIAAN RTLLMTLVDT NWFGQNTPAI ATTESQYAEM 181 WAQDAAAMYG YASAAAPATV LTPFAPPPQT TNATGLVGHA TAVAALRGQH SWAAAIPWSD 241 IQKYWMMFLG ALATAEGFIY DSGGLTLNAL QFVGGMLWST ALAEAGAAEA AAGAGGAAGW 301 SAWSQLGAGP VAASATLAAK IGPMSVPPGW SAPPATPQAQ TVARSIPGIR SAAEAAETSV 361 LLRGAPTPGR SRAAHMGRRY GRRLTVMADR PNVG //