LOCUS       SIU00326.1               587 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            DNA repair protein recN (Recombination protein N) protein.
ACCESSION   LT708304-1739
PROTEIN_ID  SIU00326.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="recN"
                     /locus_tag="BQ2027_MB1722"
                     /note="Mb1722, recN, len: 587 aa. Equivalent to Rv1696,
                     len: 587 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 587 aa overlap). Probable recN, DNA
                     repair protein, similar to many e.g. RECN_ECOLI|P05824 dna
                     repair protein recN (553 aa), FASTA scores: opt: 508, E():
                     1.9e-33, (31.5% identity in 587 aa overlap). Equivalent to
                     Z95117|MLCB1351_12 recN from Mycobacterium leprae (587
                     aa), FASTA scores: (76.1% identit y in 589 aa overlap).
                     Contains PS00017 ATP/GTP-binding site motif A (P-loop).
                     Protein product from Mb1722 detected using SWATH mass
                     spectrometry. Mb1722 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P0A5U7"
                     /db_xref="InterPro:IPR003395"
                     /db_xref="InterPro:IPR004604"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5U7"
BEGIN
        1 MLTELRIESL GAISVATAEF DRGFTVLTGE TGTGKTMVVT GLHLLGGARA DATRVRSGAD
       61 RAVVEGRFTT TDLDDATVAG LQAVLDSSGA ERDEDGSVIA LRSISRDGPS RAYLGGRGVP
      121 AKSLSGFTNE LLTLHGQNDQ LRLMRPDEQR GALDRFAAAG EAVQRYRKLR DAWLTARRDL
      181 VDRRNRAREL AQEADRLKFA LNEIDTVDPQ PGEDVALVAD IARLSELDTL REAATTARAT
      241 LCGTPDADAF DRGAVDSLGR ARAALQSSDD AALRGLAEQV GEALTVVVDA VAELGAYLDE
      301 LPADASALDA KLARQAQLRT LTRKYAADID GVLRWADEAR ARLAQLDVSE EGLAALERRT
      361 GELAHELGQA AVDLSTIRRK AAKRLAKEVS AELSALAMAD AEFTIGVTTE LADHGDPVAL
      421 ALASGELARA GADGVDAVEF GFVAHRGMTV LPLAKSASGG ELSRVMLSLE VVLATSRKQA
      481 AGTTMVFDEI DAGVGGWAAV QIGRRLARLA RTHQVIVVTH LPQVAAYADV HLMVQRTGRD
      541 GASGVRRLTS EDRVAELARM LAGLGDSDSG RAHARELLET AQNDELT
//