LOCUS SIU00326.1 587 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable DNA repair protein recN (Recombination protein N) protein. ACCESSION LT708304-1739 PROTEIN_ID SIU00326.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="recN" /locus_tag="BQ2027_MB1722" /note="Mb1722, recN, len: 587 aa. Equivalent to Rv1696, len: 587 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 587 aa overlap). Probable recN, DNA repair protein, similar to many e.g. RECN_ECOLI|P05824 dna repair protein recN (553 aa), FASTA scores: opt: 508, E(): 1.9e-33, (31.5% identity in 587 aa overlap). Equivalent to Z95117|MLCB1351_12 recN from Mycobacterium leprae (587 aa), FASTA scores: (76.1% identit y in 589 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Protein product from Mb1722 detected using SWATH mass spectrometry. Mb1722 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P0A5U7" /db_xref="InterPro:IPR003395" /db_xref="InterPro:IPR004604" /db_xref="InterPro:IPR027417" /db_xref="UniProtKB/Swiss-Prot:P0A5U7" BEGIN 1 MLTELRIESL GAISVATAEF DRGFTVLTGE TGTGKTMVVT GLHLLGGARA DATRVRSGAD 61 RAVVEGRFTT TDLDDATVAG LQAVLDSSGA ERDEDGSVIA LRSISRDGPS RAYLGGRGVP 121 AKSLSGFTNE LLTLHGQNDQ LRLMRPDEQR GALDRFAAAG EAVQRYRKLR DAWLTARRDL 181 VDRRNRAREL AQEADRLKFA LNEIDTVDPQ PGEDVALVAD IARLSELDTL REAATTARAT 241 LCGTPDADAF DRGAVDSLGR ARAALQSSDD AALRGLAEQV GEALTVVVDA VAELGAYLDE 301 LPADASALDA KLARQAQLRT LTRKYAADID GVLRWADEAR ARLAQLDVSE EGLAALERRT 361 GELAHELGQA AVDLSTIRRK AAKRLAKEVS AELSALAMAD AEFTIGVTTE LADHGDPVAL 421 ALASGELARA GADGVDAVEF GFVAHRGMTV LPLAKSASGG ELSRVMLSLE VVLATSRKQA 481 AGTTMVFDEI DAGVGGWAAV QIGRRLARLA RTHQVIVVTH LPQVAAYADV HLMVQRTGRD 541 GASGVRRLTS EDRVAELARM LAGLGDSDSG RAHARELLET AQNDELT //