LOCUS       SIU00322.1               353 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            PHOSPHATASE protein.
ACCESSION   LT708304-1735
PROTEIN_ID  SIU00322.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1718"
                     /note="Mb1718, -, len: 353 aa. Equivalent to Rv1692, len:
                     353 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 353 aa overlap). Probable phosphatase
                     (EC 3.1.-.-), some similarity to others e.g.
                     PNPP_SCHPO|Q00472 4-nitrophenylphosphatase (269 aa), FASTA
                     scores: opt: 214, E(): 1.3e-10, (29.5% identity in 241 aa
                     overlap); and to NAGD_ECOLI|P15302 nagd protein from
                     Escherichia coli (250 aa), FASTA scores: opt: 314, E():
                     9.8e-08, (28.2% identity in 245 aa overlap). Also similar
                     to AL109848|SCI51.28 hypothetical protein from
                     Streptomyces coelicolor (343 aa), FASTA scores: opt: 768,
                     E(): 0, (44.8% identity in 315 aa overlap). Protein
                     product from Mb1718 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1718 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="InterPro:IPR006357"
                     /db_xref="InterPro:IPR023214"
                     /db_xref="InterPro:IPR036412"
                     /db_xref="InterPro:IPR041065"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZ15"
BEGIN
        1 MKSIAQEHDC LLIDLDGTVF CGRQPTGGAV QSLSQVRSRK LFVTNNASRS ADEVAAHLCE
       61 LGFTATGEDV VTSAQSAAHL LAGQLAPGAR VLIVGTEALA NEVAAVGLRP VRRFEDRPDA
      121 VVQGLSMTTG WSDLAEAALA IRAGALWVAA NVDPTLPTER GLLPGNGSMV AALRTATGMD
      181 PRVAGKPAPA LMTEAVARGD FRAALVVGDR LDTDIEGANA AGLPSLMVLT GVNSAWDAVY
      241 AEPVRRPTYI GHDLRSLHQD SKLLAVAPQP GWQIDVGGGA VTVCANGDVD DLEFIDDGLS
      301 IVRAVASAVW EARAADLHQR PLRIEAGDER ARAALQRWSL MRSDHPVTSV GTQ
//