LOCUS SIU00322.1 353 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE PHOSPHATASE protein. ACCESSION LT708304-1735 PROTEIN_ID SIU00322.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1718" /note="Mb1718, -, len: 353 aa. Equivalent to Rv1692, len: 353 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 353 aa overlap). Probable phosphatase (EC 3.1.-.-), some similarity to others e.g. PNPP_SCHPO|Q00472 4-nitrophenylphosphatase (269 aa), FASTA scores: opt: 214, E(): 1.3e-10, (29.5% identity in 241 aa overlap); and to NAGD_ECOLI|P15302 nagd protein from Escherichia coli (250 aa), FASTA scores: opt: 314, E(): 9.8e-08, (28.2% identity in 245 aa overlap). Also similar to AL109848|SCI51.28 hypothetical protein from Streptomyces coelicolor (343 aa), FASTA scores: opt: 768, E(): 0, (44.8% identity in 315 aa overlap). Protein product from Mb1718 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1718 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR006357" /db_xref="InterPro:IPR023214" /db_xref="InterPro:IPR036412" /db_xref="InterPro:IPR041065" /db_xref="UniProtKB/TrEMBL:A0A1R3XZ15" BEGIN 1 MKSIAQEHDC LLIDLDGTVF CGRQPTGGAV QSLSQVRSRK LFVTNNASRS ADEVAAHLCE 61 LGFTATGEDV VTSAQSAAHL LAGQLAPGAR VLIVGTEALA NEVAAVGLRP VRRFEDRPDA 121 VVQGLSMTTG WSDLAEAALA IRAGALWVAA NVDPTLPTER GLLPGNGSMV AALRTATGMD 181 PRVAGKPAPA LMTEAVARGD FRAALVVGDR LDTDIEGANA AGLPSLMVLT GVNSAWDAVY 241 AEPVRRPTYI GHDLRSLHQD SKLLAVAPQP GWQIDVGGGA VTVCANGDVD DLEFIDDGLS 301 IVRAVASAVW EARAADLHQR PLRIEAGDER ARAALQRWSL MRSDHPVTSV GTQ //