LOCUS SIU00320.1 139 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE LIPOPROTEIN LPRJ protein. ACCESSION LT708304-1733 PROTEIN_ID SIU00320.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="lprJ" /locus_tag="BQ2027_MB1716" /note="Mb1716, lprJ, len: 139 aa. Equivalent to Rv1690, len: 127 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 124 aa overlap). Probable lprJ, lipoprotein, contains possible signal sequence and PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Weakly similar to other Mycobacterium tuberculosis hypothetical proteins with conserved cysteines e.g. Rv1804c, Rv1810, Rv3354, etc. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 2 bp insertion (*-ac) at the 5' end, leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (139 aa versus 127 aa). Mb1716 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:A0A1R3XZ22" /db_xref="InterPro:IPR007969" /db_xref="UniProtKB/TrEMBL:A0A1R3XZ22" BEGIN 1 MTQVRQQREA GDDGTHTHDG TRTWRTGRQA TTLLALLAGV FGGAASCAAP IQADMMGNAF 61 LTALTNAGIA YDQPATTVAL GRSVCPMVVA PGGTFESITS RMAEINGMSR DMASTFTIVA 121 IGTYCPAVIA PLMPNRLQA //