LOCUS       SIU00318.1               203 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            3-methyladenine dna glycosylase mpg protein.
ACCESSION   LT708304-1731
PROTEIN_ID  SIU00318.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="mpg"
                     /locus_tag="BQ2027_MB1714"
                     /note="Mb1714, -, len: 203 aa. Equivalent to Rv1688, len:
                     203 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 203 aa overlap). Possible
                     3-methyladenine DNA glycosylase (EC 3.2.2.-), similar to
                     several eukaryotic 3-methylpurine DNA glycosylases and
                     3-methyladenine DNA glycosylases e.g. Q39147|X76169
                     3-METHYLADENINE GLYCOSYLASE from Arabidobsis thaliana (254
                     aa), FASTA scores: opt: 297, E(): 8.3e-15, (31.8% identity
                     in 198 aa overlap) and P29372|3MG_HUMAN
                     dna-3-methyladenine glycosidase (298 aa), FASTA scores:
                     opt: 220, E(): 7.2e-05, (36.4% identity in 184 aa
                     overlap). BELONGS TO THE MPG FAMILY OF DNA GLYCOSYLASES.
                     Protein product from Mb1714 detected using SWATH mass
                     spectrometry."
                     /db_xref="GOA:P65413"
                     /db_xref="InterPro:IPR003180"
                     /db_xref="InterPro:IPR011034"
                     /db_xref="InterPro:IPR036995"
                     /db_xref="UniProtKB/Swiss-Prot:P65413"
BEGIN
        1 MNAEELAIDP VAAAHRLLGA TIAGRGVRAM VVEVEAYGGV PDGPWPDAAA HSYRGRNGRN
       61 DVMFGPPGRL YTYRSHGIHV CANVACGPDG TAAAVLLRAA AIEDGAELAT SRRGQTVRAV
      121 ALARGPGNLC AALGITMADN GIDLFDPSSP VRLRLNDTHR ARSGPRVGVS QAADRPWRLW
      181 LTGRPEVSAY RRSSRAPARG ASD
//