LOCUS SIU00318.1 203 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 possible 3-methyladenine dna glycosylase mpg protein. ACCESSION LT708304-1731 PROTEIN_ID SIU00318.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="mpg" /locus_tag="BQ2027_MB1714" /note="Mb1714, -, len: 203 aa. Equivalent to Rv1688, len: 203 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 203 aa overlap). Possible 3-methyladenine DNA glycosylase (EC 3.2.2.-), similar to several eukaryotic 3-methylpurine DNA glycosylases and 3-methyladenine DNA glycosylases e.g. Q39147|X76169 3-METHYLADENINE GLYCOSYLASE from Arabidobsis thaliana (254 aa), FASTA scores: opt: 297, E(): 8.3e-15, (31.8% identity in 198 aa overlap) and P29372|3MG_HUMAN dna-3-methyladenine glycosidase (298 aa), FASTA scores: opt: 220, E(): 7.2e-05, (36.4% identity in 184 aa overlap). BELONGS TO THE MPG FAMILY OF DNA GLYCOSYLASES. Protein product from Mb1714 detected using SWATH mass spectrometry." /db_xref="GOA:P65413" /db_xref="InterPro:IPR003180" /db_xref="InterPro:IPR011034" /db_xref="InterPro:IPR036995" /db_xref="UniProtKB/Swiss-Prot:P65413" BEGIN 1 MNAEELAIDP VAAAHRLLGA TIAGRGVRAM VVEVEAYGGV PDGPWPDAAA HSYRGRNGRN 61 DVMFGPPGRL YTYRSHGIHV CANVACGPDG TAAAVLLRAA AIEDGAELAT SRRGQTVRAV 121 ALARGPGNLC AALGITMADN GIDLFDPSSP VRLRLNDTHR ARSGPRVGVS QAADRPWRLW 181 LTGRPEVSAY RRSSRAPARG ASD //