LOCUS SIU00312.1 305 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable coiled-coil structural protein protein. ACCESSION LT708304-1725 PROTEIN_ID SIU00312.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1709" /note="Mb1709, -, len: 305 aa. Equivalent to Rv1682, len: 305 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 305 aa overlap). Probable coiled-coil structural protein, weakly similar to many paramyosins, kinesins and plectins e.g. MYSP_ONCVO|Q02171 paramyosin from onchocerca volvulus (879 aa), fasta scores: opt: 180, E():2.6e-08, (24.4% identity in 234 aa overlap). Also similar to Mycobacterium tuberculosis hypothetical coiled-coil proteins (wag31 antigen 84) Rv2145c and Rv2927c. Mb1709 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR007793" /db_xref="UniProtKB/TrEMBL:A0A1R3XZ06" BEGIN 1 MLPQRPNCTK LFRPRRGVSE RYRVTTAHNG SAPRFQRTRS GYDPVAVNHY IAELVLRQQA 61 QHCEIETLKA EIASLKDENA ALKDTSPSAQ AVTDRMAKML RLAVDEVFQM QSEARAEAAT 121 LVSAARDEAE AVRTQKREML ADMNARQRAL ESEHADVMRR AREEAEQLVA QATAEVERMR 181 VIDARRREKA EQELDAEIIR LRTDAQFQID DQLQATQQEC EKRLGEAKIE ADRRLHVADE 241 QIEHGLSEAR RTLEEISQRR VGILEQLARI HAQLENIPAL LESARHSETE PLQSINGAVA 301 ELRAI //