LOCUS       SIU00312.1               305 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            coiled-coil structural protein protein.
ACCESSION   LT708304-1725
PROTEIN_ID  SIU00312.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1709"
                     /note="Mb1709, -, len: 305 aa. Equivalent to Rv1682, len:
                     305 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 305 aa overlap). Probable coiled-coil
                     structural protein, weakly similar to many paramyosins,
                     kinesins and plectins e.g. MYSP_ONCVO|Q02171 paramyosin
                     from onchocerca volvulus (879 aa), fasta scores: opt: 180,
                     E():2.6e-08, (24.4% identity in 234 aa overlap). Also
                     similar to Mycobacterium tuberculosis hypothetical
                     coiled-coil proteins (wag31 antigen 84) Rv2145c and
                     Rv2927c. Mb1709 found to be expressed during exponential
                     growth in Sauton's minimal media by RNA-sequencing (TPM >
                     20)."
                     /db_xref="InterPro:IPR007793"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZ06"
BEGIN
        1 MLPQRPNCTK LFRPRRGVSE RYRVTTAHNG SAPRFQRTRS GYDPVAVNHY IAELVLRQQA
       61 QHCEIETLKA EIASLKDENA ALKDTSPSAQ AVTDRMAKML RLAVDEVFQM QSEARAEAAT
      121 LVSAARDEAE AVRTQKREML ADMNARQRAL ESEHADVMRR AREEAEQLVA QATAEVERMR
      181 VIDARRREKA EQELDAEIIR LRTDAQFQID DQLQATQQEC EKRLGEAKIE ADRRLHVADE
      241 QIEHGLSEAR RTLEEISQRR VGILEQLARI HAQLENIPAL LESARHSETE PLQSINGAVA
      301 ELRAI
//