LOCUS       SIU00311.1               330 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MOEX protein.
ACCESSION   LT708304-1724
PROTEIN_ID  SIU00311.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="moeX"
                     /locus_tag="BQ2027_MB1708"
                     /note="Mb1708, moeX, len: 330 aa. Equivalent to Rv1681,
                     len: 330 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 330 aa overlap). Possible moeX,
                     Molybdopterin biosynthesis protein, has weak similarity to
                     MOAA_ECOLI|P30745 molybdenum cofactor biosynthesis protein
                     (329 aa), FASTA scores: opt: 162, E(): 0.00081, (27.7%
                     identity in 224 aa overlap) and to Rv3109|MTCY164.19 MoaA
                     from Mycobacterium tuberculosis (28.5% identity in 165 aa
                     overlap). Mb1708 found to be expressed during exponential
                     growth in Sauton's minimal media by RNA-sequencing (TPM >
                     20)."
                     /db_xref="GOA:A0A1R3XYY9"
                     /db_xref="InterPro:IPR007197"
                     /db_xref="InterPro:IPR013785"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYY9"
BEGIN
        1 MIIELMRRVV GLAQGATAEV AVYGDRDRDL AERWCANTGN TLVRADVDQT GVGTLVVRRG
       61 HPPDPASVLG PDRLPGVRLW LYTNFHCNLC CDYCCVSSSP STPHRELGAE RIGRIVGEAA
      121 RWGVRELFLT GGEPFLLPDI DTIIATCVKQ LPTTVLTNGM VFKGRGRRAL ESLPRGLALQ
      181 ISLDSATPEL HDAHRGAGTW VKAVAGIRLA LSLGFRVRVA ATVASPAPGE LTAFHDFLDG
      241 LGIAPGDQLV RPIALEGAAS QGVALTRESL VPEVTVTADG VYWHPVAATD ERALVTRTVE
      301 PLTPALDMVS RLFAEQWTRA AEEAALFPCA
//