LOCUS       SIU00309.1               373 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            ACYL-COA DEHYDROGENASE FADE16 protein.
ACCESSION   LT708304-1722
PROTEIN_ID  SIU00309.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="fadE16"
                     /locus_tag="BQ2027_MB1706"
                     /note="Mb1706, fadE16, len: 373 aa. Equivalent to Rv1679,
                     len: 373 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 373 aa overlap). Possible fadE16,
                     acyl-CoA dehydrogenase (EC 1.3.99.-), similar to
                     acyl/butyryl-CoA dehydrogenases e.g. NP_244665.1|NC_002570
                     acyl-CoA dehydrogenase from Bacillus halodurans (380 aa);
                     NP_000008.1|NM_000017 acyl-Coenzyme A dehydrogenase from
                     Homo sapiens (412 aa); Z99113|BSUB0010_119 from Bacillus
                     subtilis (380 aa), FASTA scores: opt: 439, E(): 3.4e-20,
                     (29.6% identity in 287 aa overlap); etc. Weakly similar to
                     many dehydrogenases and to P31571|CAIA_ECOLI probable
                     carnitine operon oxidoreductase from Escherichia coli (380
                     aa), FASTA scores: opt: 109, E(): 0.0066, (28.6% identity
                     in 98 aa overlap). Protein product from Mb1706 detected
                     using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb1706 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XZ09"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR009075"
                     /db_xref="InterPro:IPR009100"
                     /db_xref="InterPro:IPR013786"
                     /db_xref="InterPro:IPR036250"
                     /db_xref="InterPro:IPR037069"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZ09"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MATPGVVQEV VSVAAEHAER VDTDCAFPAE AVDALRKTGL LGLVLPREIG GMGSGPVEFT
       61 EVVAQLSAAC GSTAMIYLMH MAAAVTVAAS PPPGLPDLLA DMASGKQLGT LAFSEPGSRS
      121 HFWAPVSTAS ADGDGIAVRA DKSWVTSAGF ADVYVVSVGS ADGAAGDVDL YAVPADTPGL
      181 RVAGTFTGMG LRGNASAPMA VDIRIPDSYR LGEAGGGFGI MMQTVLPWFN LGNAAVSLGL
      241 ATAATGAAVK HVGTARLEHL GGSLAELPTI RAQIARMGTT LAAQKAYLEV AANSVSSPDD
      301 TTLTHVLGVK ASVNDAALTI TESAMRVCGG AAFSKHLPIE RAFRDARAGS VMAPTADALY
      361 DFYGRAVTGL PLF
//