LOCUS       SIU00288.1               170 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            Arginine repressor argR (AHRC) protein.
ACCESSION   LT708304-1701
PROTEIN_ID  SIU00288.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="argR"
                     /locus_tag="BQ2027_MB1685"
                     /standard_name="ahrC"
                     /note="Mb1685, argR, len: 170 aa. Equivalent to Rv1657,
                     len: 170 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 170 aa overlap). Probable argR, Arginine
                     repressor (alternate gene name: ahrC). Similar to
                     AHRC_BACSU|P17893 arginine hydroximate resistance protein
                     from Bacillus subtilis (149 aa), FASTA scores: opt: 283,
                     E(): 1.8e-11, (34.5% identity in 142 aa overlap); and
                     ARGR_ECOLI|P15282 arginine repressor from Escherichia coli
                     (156 aa), FASTA scores: opt: 194, E(): 6.4e-06, (30.8%
                     identity in 146 aa overlap). BELONGS TO THE ARGR FAMILY.
                     Protein product from Mb1685 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1685 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:P0A4Y9"
                     /db_xref="InterPro:IPR001669"
                     /db_xref="InterPro:IPR020899"
                     /db_xref="InterPro:IPR020900"
                     /db_xref="InterPro:IPR036251"
                     /db_xref="InterPro:IPR036388"
                     /db_xref="InterPro:IPR036390"
                     /db_xref="UniProtKB/Swiss-Prot:P0A4Y9"
BEGIN
        1 MSRAKAAPVA GPEVAANRAG RQARIVAILS SAQVRSQNEL AALLAAEGIE VTQATLSRDL
       61 EELGAVKLRG ADGGTGIYVV PEDGSPVRGV SGGTDRMARL LGELLVSTDD SGNLAVLRTP
      121 PGAAHYLASA IDRAALPQVV GTIAGDDTIL VVAREPTTGA QLAGMFENLR
//