LOCUS SIU00281.1 831 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 probable phenylalanyl-trna synthetase, beta chain phet protein. ACCESSION LT708304-1694 PROTEIN_ID SIU00281.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="pheT" /locus_tag="BQ2027_MB1677" /note="Mb1677, pheT, len: 831 aa. Equivalent to Rv1650, len: 831 aa, from Mycobacterium tuberculosis strain H37Rv, (99.9% identity in 831 aa overlap). pheT, Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20), similar to several e.g. SYFB_ECOLI|P07395 from Escherichia coli (795 aa), FASTA scores: opt: 995, E(): 0, (31.8% identity in 847 aa overlap). BELONGS TO THE PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN FAMILY - SUBFAMILY 1. Protein product from Mb1677 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1677 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:Q7VEV3" /db_xref="InterPro:IPR002547" /db_xref="InterPro:IPR004532" /db_xref="InterPro:IPR005121" /db_xref="InterPro:IPR005146" /db_xref="InterPro:IPR005147" /db_xref="InterPro:IPR009061" /db_xref="InterPro:IPR012340" /db_xref="InterPro:IPR020825" /db_xref="InterPro:IPR033714" /db_xref="InterPro:IPR036690" /db_xref="InterPro:IPR041616" /db_xref="UniProtKB/Swiss-Prot:Q7VEV3" BEGIN 1 MRLPYSWLRE VVAVGASGWD VTPGELEQTL LRIGHEVEEV IPLGPVDGPV TVGRVADIEE 61 LTGYKKPIRA CAVDIGDRQY REIICGATNF AVGDLVVVAL PGATLPGGFT ISARKAYGRN 121 SDGMICSAAE LNLGADHSGI LVLPPGAAEP GADGAGVLGL DDVVFHLAIT PDRGYCMSVR 181 GLARELACAY DLDFVDPASN SRVPPLPIEG PVWPLTVQPE TGVRRFALRP VIGIDPAAVS 241 PWWLQRRLLL CGIRATCPAV DVTNYVMLEL GHPMHAHDRN RISGTLGVRF ARSGETAVTL 301 DGIERKLDTA DVLIVDDAAT AAIGGVMGAA STEVRADSTD VLLEAAIWDP AAVSRTQRRL 361 HLPSEAARRY ERTVDPAISV AALDRCARLL ADIAGGEVSP TLTDWRGDPP CDDWSPPPIR 421 MGVDVPDRIA GVAYPQGTTA RRLAQIGAVV THDGDTLTVT PPSWRPDLRQ PADLVEEVLR 481 LEGLEVIPSV LPPAPAGRGL TAGQQRRRTI GRSLALSGYV EILPTPFLPA GVFDLWGLEA 541 DDSRRMTTRV LNPLEADRPQ LATTLLPALL EALVRNVSRG LVDVALFAIA QVVQPTEQTR 601 GVGLIPVDRR PTDDEIAMLD ASLPRQPQHV AAVLAGLREP RGPWGPGRPV EAADAFEAVR 661 IIARASRVDV TLRPAQYLPW HPGRCAQVFV GESSVGHAGQ LHPAVIERSG LPKGTCAVEL 721 NLDAIPCSAP LPAPRVSPYP AVFQDVSLVV AADIPAQAVA DAVRAGAGDL LEDIALFDVF 781 TGPQIGEHRK SLTFALRFRA PDRTLTEDDA SAARDAAVQS AAERVGAVLR G //