LOCUS SIU00275.1 260 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Possible 23S rRNA methyltransferase tsnR protein. ACCESSION LT708304-1688 PROTEIN_ID SIU00275.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="tsnR" /locus_tag="BQ2027_MB1671" /note="Mb1671, tsnR, len: 260 aa. Equivalent to Rv1644, len: 260 aa, from Mycobacterium tuberculosis strain H37Rv, (99.6% identity in 260 aa overlap). Possible tsnR, 23S rRNA methyltransferase (EC 2.1.1.-), similar to several e.g. TSNR_STRLU|P52393 from Streptomyces laurentii (270 aa), FASTA scores: opt: 276, E(): 3.6e-11, (27.6% identity in 261 aa overlap). Also similar to M. tuberculosis hypothetical proteins Rv0881, Rv3579c, and Rv0380c. Protein product from Mb1671 detected using SWATH mass spectrometry. Mb1671 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XYX1" /db_xref="InterPro:IPR001537" /db_xref="InterPro:IPR013123" /db_xref="InterPro:IPR029026" /db_xref="InterPro:IPR029028" /db_xref="InterPro:IPR029064" /db_xref="UniProtKB/TrEMBL:A0A1R3XYX1" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MLTERSARVA TAVKLHRHVG RRRAGRFLAE GPNLVAAALA RGLVREVFVT EVAARRHELL 61 LAAHEASVHL VTERAAKALS DTVTPAGLVA VCDLPATRLE DVLAGSPQLI AVTVEIREPG 121 NAGTVIRIAD AMGAAAVILA GRSVDPYNGK CLRASTGSIF AIPVVVAPDV GAAIADLRAA 181 GLQVLATAVD GEMALDDADR LLAEPTAWLF GPEAHGLSAE IAALADHRVH IPMSGGAESL 241 NVAAAAAICL YESARALGRR //