LOCUS       SIU00266.1               146 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 iron-
            regulated universal stress protein family protein tb15.3
            protein.
ACCESSION   LT708304-1679
PROTEIN_ID  SIU00266.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="TB15.3"
                     /locus_tag="BQ2027_MB1662"
                     /note="Mb1662, TB15.3, len: 146 aa. Equivalent to Rv1636,
                     len: 146 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 146 aa overlap). TB15.3, conserved
                     hypothetical protein (see citations below), similar to
                     other hypothetical proteins from diverse organisms e.g.
                     Q57951|MJ0531|Y531_METJA from Methanococcus jannaschii
                     (170 aa), FASTA scores: opt: 188, E(): 6e-06, (32.2%
                     identity in 149 aa overlap); also P42297|YXIE_BACSU
                     hypothetical 15.9 kd protein in bglh-wapa intergenic
                     region precursor from Bacillus subtilis (148 aa), FASTA
                     scores: opt: 162, E(): 0.00025, (30.8% identity in 156 aa
                     overlap). Part of family of Mycobacterium tuberculosis
                     hypothetical proteins (but lacks C-terminal region)
                     including Rv2005c, Rv2623, Rv2026c, Rv1996, etc. Protein
                     product from Mb1662 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1662 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="InterPro:IPR006015"
                     /db_xref="InterPro:IPR006016"
                     /db_xref="InterPro:IPR014729"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZ92"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MSAYKTVVVG TDGSDSSMRA VDRAAQIAGA DAKLIIASAY LPQHEDARAA DILKDESYKV
       61 TGTAPIYEIL HDAKERAHNA GAKNVEERPI VGAPVDALVN LADEEKADLL VVGNVGLSTI
      121 AGRLLGSVPA NVSRRAKVDV LIVHTT
//