LOCUS       SIU00252.1               346 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            integral membrane cytochrome D ubiquinol oxidase (subunit
            II) cydB (Cytochrome BD-I oxidase subunit II) protein.
ACCESSION   LT708304-1665
PROTEIN_ID  SIU00252.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="cydB"
                     /locus_tag="BQ2027_MB1648C"
                     /note="Mb1648c, cydB, len: 346 aa. Equivalent to Rv1622c,
                     len: 346 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 346 aa overlap). Probable cydB,
                     cytochrome D ubiquinol oxidase subunit II (EC 1.10.3.-),
                     integral membrane protein, similar to others e.g.
                     P11027|CYDB_ECOLI CYTOCHROME D UBIQUINOL OXIDASE SUBUNIT
                     II from Escherichia coli strain K12 (379 aa), FASTA
                     scores: opt: 519, E(): 0, (32.3% identity in 372 aa
                     overlap); P94365|CYDB_BACSU CYTOCHROME D UBIQUINOL OXIDASE
                     SUBUNIT II from Bacillus subtilis (338 aa), FASTA scores:
                     opt: 824, E(): 0, (39.5% identity in 337 aa overlap); etc.
                     Protein product from Mb1648c detected using SWATH mass
                     spectrometry. Mb1648c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XYU5"
                     /db_xref="InterPro:IPR003317"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYU5"
BEGIN
        1 MVLQELWFGV IAALFLGFFI LEGFDFGVGM LMAPFAHVGM GDPETHRRTA LNTIGPVWDG
       61 NEVWLITAGA AIFAAFPGWY ATVFSALYLP LLAILFGMIL RAVAIEWRGK IDDPKWRTGA
      121 DFGIAAGSWL PALLWGVAFA ILVRGLPVDA NGHVALSIPD VLNAYTLLGG LATAGLFSLY
      181 GAVFIALKTS GPIRDDAYRF AVWLSLPVAG LVAGFGLWTQ LAYGKDWTWL VLAVAGCAQA
      241 AATVLVWRRV SDGWAFMCTL IVVAAVVVLL FGALYPNLVP STLNPQWSLT IHNASSTPYT
      301 LKIMTWVTAF FAPLTVAYQT WTYWVFRQRI SAERIPPPTG LARRAP
//