LOCUS       SIU00251.1               527 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            'COMPONENT LINKED WITH THE ASSEMBLY OF CYTOCHROME' TRANSPORT
            TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER CYDD
            protein.
ACCESSION   LT708304-1664
PROTEIN_ID  SIU00251.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="cydD"
                     /locus_tag="BQ2027_MB1647C"
                     /note="Mb1647c, cydD, len: 527 aa. Equivalent to Rv1621c,
                     len: 527 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 527 aa overlap). Probable cydD,
                     transmembrane ATP-binding protein ABC transporter involved
                     in transport of component linked with the assembly of
                     cytochrome (see citation below), similar to others e.g.
                     P94366|CYDC_BACSU TRANSPORT ATP-BINDING PROTEIN from
                     Bacillus subtilis (567 aa), FASTA scores: opt: 784, E():
                     0, (30.1% identity in 535 aa overlap); N-terminal part of
                     AL034355|SCD78_14 from Streptomyces coelicolor (1172 aa),
                     FASTA scores: opt: 1295, E(): 0, (44.6% identity in 534 aa
                     overlap); etc. Also similar to Q11019|Y07D_MYCTU from
                     Mycobacterium tuberculosis (579 aa), FASTA scores: opt:
                     530, E(): 6.9e-25, (29.1% identity in 530 aa overlap).
                     Contains (PS00211) ABC transporters family signature, and
                     (PS00017) ATP/GTP-binding site motif A (P-loop). BELONGS
                     TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC
                     TRANSPORTERS). Mb1647c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XYT5"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="InterPro:IPR014216"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="InterPro:IPR036640"
                     /db_xref="InterPro:IPR039421"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYT5"
BEGIN
        1 MACGVGISGC AIGSAIVLAS IVAGVIDPAN PGMAGLRRWL GPLSILLVLW GLRASIQWLQ
       61 ARLAQRGASA VIADLSGQVL TAVTARRPSQ LAAQRDAAAV LITRGLDGLR PYFTGYLPTL
      121 LLAAILTPAT VAVIGLYDLK SMAIVVITLP LIPIFMVLIG LATTNPSAAA LAAMTAVQAR
      181 LLDLIAGIPT LRALGRASGP EQRIAELSAD HRRSAMATLR IAFLSALVLE LLATLGVALV
      241 AVGIGLRLVF GEMSLTAGLT VLLLAPEVYW PLRRVGVQFH AAADGRTAAD KAFALLGESP
      301 SPTPGRRTVT ARGGVIRLER LSVRGRDGRA PYDLTADIEP GRVTVLTGRN GAGKSTTLQA
      361 IAGLTAPSSG RITVAGVDVT NLAPAAWWRQ LSWLPQRPVL VPGTVRHNLV LLGPVDDLER
      421 ACAAAGFDAV LDELPRGLDT VLGRGGVGLS LGQRQRLGLA RALGSPAAVL LLDEPTAHLD
      481 ARTEQHVLGA IVERARAGAT VLVVAHRQQV AAAGDRVVEV NSDGFRR
//