LOCUS       SIU00250.1               576 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            'COMPONENT LINKED WITH THE ASSEMBLY OF CYTOCHROME' TRANSPORT
            TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER CYDC
            protein.
ACCESSION   LT708304-1663
PROTEIN_ID  SIU00250.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="cydC"
                     /locus_tag="BQ2027_MB1646C"
                     /note="Mb1646c, cydC, len: 576 aa. Equivalent to Rv1620c,
                     len: 576 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 576 aa overlap). Probable cydC,
                     transmembrane ATP-binding protein ABC transporter involved
                     in transport of component linked with the assembly of
                     cytochrome (see citation below), similar to others e.g.
                     CYDC_ECOLI|P23886 transport ATP-binding protein from
                     Escherichia coli (573 aa), FASTA scores: opt: 631, E():
                     1.6e-30, (28.5% identity in 569 aa overlap); C-terminal
                     part of AL034355|SCD78_14 from Streptomyces coelicolor
                     (1172 aa), FASTA scores: opt: 956, E(): 0, (38.8% identity
                     in 554 aa overlap); etc. Contains (PS00211) ABC
                     transporters family signature, and (PS00017)
                     ATP/GTP-binding site motif A (P-loop). BELONGS TO THE
                     ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS).
                     Mb1646c found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XYV3"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="InterPro:IPR014223"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="InterPro:IPR036640"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYV3"
BEGIN
        1 MNRPSAVSRR QRDLLAASGL LGPRLPRILA AVALGVLSLG SALALAGVSA WLITRAWQMP
       61 PVLDLSVAVV AVRAFAISRG VLHYCERLAT HDTALRAAGR ARTLIYHRLA HGPAAAAVGL
      121 HSGDLAARVG ADVDELANML VRALVPIAVA AVLAVAATAV VAAVSVPAAV VLAVCLLVAG
      181 VVAPWLAGRT AAAQEAIARQ HRGMRDTSAM IALEHAPELR VAGALRNVIA DSQRRQHAWA
      241 DALDAAARTG AIAEAMPTAA IGASLLGAVV AGIGMAPTVA PTTLAILMLL PLSAFEATVA
      301 LPAAAVQLTR SRIAAARLLD LTGSNRVRET ESTVSARLPV GTGVLAADVC CGHQEAQSIR
      361 VTIDLPPGAR LAVTGASGAG KTTLLMTLAG LLPPVHGRVL LDGTNLSDFD EDELRSAVSF
      421 FAEDAHIFAT TVRDNLLTAR GDCPDDELIE ALDRVGLCGW LAGLPEGLST VLIGGAQAVS
      481 AGQRRRLLLA RAVLSPARIV LLDEPVEHLD AANADLLRDL LAPNSGIMSA MRTVVVATHH
      541 LPNDIQCAEL SIATDQRCRR RGTNSSDNNT NASAKT
//