LOCUS SIU00244.1 468 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Possible prolipoprotein diacylglyceryl transferases Lgt protein. ACCESSION LT708304-1657 PROTEIN_ID SIU00244.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="lgt" /locus_tag="BQ2027_MB1640" /note="Mb1640, lgt, len: 468 aa. Equivalent to Rv1614, len: 468 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 468 aa overlap). Possible lgt, prolipoprotein diacylglyceryl transferases (EC 2.4.99.-), similar to many prolipoprotein diacylglyceryl transferases. FASTA scores: LGT_STAAU|P52282 prolipoprotein diacylglyceryl transferase from Staphylococcus aureus subsp. (279 aa), opt: 289, E():3.6e-09, (31.5% identity in 257 aa overlap); AL096884|SC4G6_3 cosmid 4G6 from Streptomyces coelicolor (343 aa), opt: 735, E(): 4e-32, (46.5% identity in 391 aa overlap). Protein product from Mb1640 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1640 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:Q7VEW5" /db_xref="InterPro:IPR001640" /db_xref="UniProtKB/Swiss-Prot:Q7VEW5" BEGIN 1 MRMLPSYIPS PPRGVWYLGP LPVRAYAVCV ITGIIVALLI GDRRLTARGG ERGMTYDIAL 61 WAVPFGLIGG RLYHLATDWR TYFGDGGAGL AAALRIWDGG LGIWGAVTLG VMGAWIGCRR 121 CGIPLPVLLD AVAPGVVLAQ AIGRLGNYFN QELYGRETTM PWGLEIFYRR DPSGFDVPNS 181 LDGVSTGQVA FVVQPTFLYE LIWNVLVFVA LIYIDRRFII GHGRLFGFYV AFYCAGRFCV 241 ELLRDDPATL IAGIRINSFT STFVFIGAVV YIILAPKGRE APGALRGSEY VVDEALEREP 301 AELAAAAVAS AASAVGPVGP GEPNQPDDVA EAVKAEVAEV TDEVAAESVV QVADRDGEST 361 PAVEETSEAD IEREQPGDLA GQAPAAHQVD AEAASAAPEE PAALASEAHD ETEPEVPEKA 421 APIPDPAKPD ELAVAGPGDD PAEPDGIRRQ DDFSSRRRRW WRLRRRRQ //