LOCUS       SIU00244.1               468 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Possible
            prolipoprotein diacylglyceryl transferases Lgt protein.
ACCESSION   LT708304-1657
PROTEIN_ID  SIU00244.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lgt"
                     /locus_tag="BQ2027_MB1640"
                     /note="Mb1640, lgt, len: 468 aa. Equivalent to Rv1614,
                     len: 468 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 468 aa overlap). Possible lgt,
                     prolipoprotein diacylglyceryl transferases (EC 2.4.99.-),
                     similar to many prolipoprotein diacylglyceryl
                     transferases. FASTA scores: LGT_STAAU|P52282
                     prolipoprotein diacylglyceryl transferase from
                     Staphylococcus aureus subsp. (279 aa), opt: 289,
                     E():3.6e-09, (31.5% identity in 257 aa overlap);
                     AL096884|SC4G6_3 cosmid 4G6 from Streptomyces coelicolor
                     (343 aa), opt: 735, E(): 4e-32, (46.5% identity in 391 aa
                     overlap). Protein product from Mb1640 detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb1640 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:Q7VEW5"
                     /db_xref="InterPro:IPR001640"
                     /db_xref="UniProtKB/Swiss-Prot:Q7VEW5"
BEGIN
        1 MRMLPSYIPS PPRGVWYLGP LPVRAYAVCV ITGIIVALLI GDRRLTARGG ERGMTYDIAL
       61 WAVPFGLIGG RLYHLATDWR TYFGDGGAGL AAALRIWDGG LGIWGAVTLG VMGAWIGCRR
      121 CGIPLPVLLD AVAPGVVLAQ AIGRLGNYFN QELYGRETTM PWGLEIFYRR DPSGFDVPNS
      181 LDGVSTGQVA FVVQPTFLYE LIWNVLVFVA LIYIDRRFII GHGRLFGFYV AFYCAGRFCV
      241 ELLRDDPATL IAGIRINSFT STFVFIGAVV YIILAPKGRE APGALRGSEY VVDEALEREP
      301 AELAAAAVAS AASAVGPVGP GEPNQPDDVA EAVKAEVAEV TDEVAAESVV QVADRDGEST
      361 PAVEETSEAD IEREQPGDLA GQAPAAHQVD AEAASAAPEE PAALASEAHD ETEPEVPEKA
      421 APIPDPAKPD ELAVAGPGDD PAEPDGIRRQ DDFSSRRRRW WRLRRRRQ
//