LOCUS       SIU00234.1               270 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            INOSITOL-MONOPHOSPHATASE IMPA (IMP) protein.
ACCESSION   LT708304-1647
PROTEIN_ID  SIU00234.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="impA"
                     /locus_tag="BQ2027_MB1630"
                     /note="Mb1630, impA, len: 270 aa. Equivalent to Rv1604,
                     len: 270 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (98.9% identity in 270 aa overlap). Probable impA,
                     inositol monophosphatase (EC 3.1.3.25), similar to many
                     e.g. AF0059|AF005905_2 inositol monophosphate phosphatase
                     from Mycobacterium smegmatis (276 aa), FASTA scores: opt:
                     1241, E(): 0, (70.5% identity in 261 aa overlap). Also
                     similar to Mycobacterium tuberculosis proteins Rv3137 and
                     Rv2701c. Mb1630 found to be expressed during exponential
                     growth in Sauton's minimal media by RNA-sequencing (TPM >
                     20)."
                     /db_xref="GOA:A0A1R3XZP5"
                     /db_xref="InterPro:IPR000760"
                     /db_xref="InterPro:IPR020550"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZP5"
BEGIN
        1 MHLDSLVAPL VEQASAILDA ATALFLVGHR ADSAVRKKGN DFATEVDLAI ERQVVAALVA
       61 ATGIEVHGEE FGGPAVDSRW VWVLDPIDGT INHAAGSPLA AILLGLLHDG VPVAGLTWMP
      121 FTDQRYTAVA GGPLIKNGVP QPPLADAELA NVLVGVGTFS ADSRGQFPGR YRLAVLEKLS
      181 RVSSRLRMHG STGIDLVFVA DGILGGAISF GGHVWDHAAG VALVRAAGGV VTDLAGQPWT
      241 PASRSALAGP LRVHAQILEI LGSIGEPEDY
//