LOCUS SIU00234.1 270 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE INOSITOL-MONOPHOSPHATASE IMPA (IMP) protein. ACCESSION LT708304-1647 PROTEIN_ID SIU00234.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="impA" /locus_tag="BQ2027_MB1630" /note="Mb1630, impA, len: 270 aa. Equivalent to Rv1604, len: 270 aa, from Mycobacterium tuberculosis strain H37Rv, (98.9% identity in 270 aa overlap). Probable impA, inositol monophosphatase (EC 3.1.3.25), similar to many e.g. AF0059|AF005905_2 inositol monophosphate phosphatase from Mycobacterium smegmatis (276 aa), FASTA scores: opt: 1241, E(): 0, (70.5% identity in 261 aa overlap). Also similar to Mycobacterium tuberculosis proteins Rv3137 and Rv2701c. Mb1630 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:A0A1R3XZP5" /db_xref="InterPro:IPR000760" /db_xref="InterPro:IPR020550" /db_xref="UniProtKB/TrEMBL:A0A1R3XZP5" BEGIN 1 MHLDSLVAPL VEQASAILDA ATALFLVGHR ADSAVRKKGN DFATEVDLAI ERQVVAALVA 61 ATGIEVHGEE FGGPAVDSRW VWVLDPIDGT INHAAGSPLA AILLGLLHDG VPVAGLTWMP 121 FTDQRYTAVA GGPLIKNGVP QPPLADAELA NVLVGVGTFS ADSRGQFPGR YRLAVLEKLS 181 RVSSRLRMHG STGIDLVFVA DGILGGAISF GGHVWDHAAG VALVRAAGGV VTDLAGQPWT 241 PASRSALAGP LRVHAQILEI LGSIGEPEDY //