LOCUS SIU00216.1 354 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable phiRv1 integrase protein. ACCESSION LT708304-1629 PROTEIN_ID SIU00216.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1612C" /note="Mb1612c, -, len: 469 aa. Equivalent to Rv1586c, len: 469 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 469 aa overlap). Probable phiRv1 integrase, possibly member of the serine family of recombinases (see citation below), similar to several bacteriophage integrases e.g. Q37839 ORF469 PROTEIN from Bacteriophage R4 (469 aa), FASTA scores: opt: 623, E(): 1.6e-29, (31.1% identity in 482 aa overlap); and Bacteriophage TP901-1. Protein product from Mb1612c detected using SWATH mass spectrometry. Mb1612c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XZ46" /db_xref="InterPro:IPR011109" /db_xref="UniProtKB/TrEMBL:A0A1R3XZ46" BEGIN 1 MATPQGRLVA RLKGSVAAHE TEHKKARQRR AARQKAERGH PNWSKAFGYL PGPNGPEPDP 61 RTAPLVKQAY ADILAGASLG DVCRQWNDAG AFTITGRPWT TTTLSKFLRK PRNAGLRAYK 121 GARYGPVDRD AIVGKAQWSP LVDEATFWAA QAVLDAPGRA PGRKSVRRHL LTGLAGCGKC 181 GNHLAGSYRT DGQVVYVCKA CHGVAILADN IEPILYHIVA ERLAMPDAVD LLRREIHDAA 241 EAETIRLELE TLYGELDRLA VERAEGLLTA RQVKISTDIV NAKITKLQAR QQDQERLRVF 301 DGIPLGTPQV AGMIAELSPD RFRAVLDVLA EVVVQPVGKS GRIFNPERVQ VNWR //