LOCUS       SIU00216.1               354 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            phiRv1 integrase protein.
ACCESSION   LT708304-1629
PROTEIN_ID  SIU00216.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1612C"
                     /note="Mb1612c, -, len: 469 aa. Equivalent to Rv1586c,
                     len: 469 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 469 aa overlap). Probable phiRv1
                     integrase, possibly member of the serine family of
                     recombinases (see citation below), similar to several
                     bacteriophage integrases e.g. Q37839 ORF469 PROTEIN from
                     Bacteriophage R4 (469 aa), FASTA scores: opt: 623, E():
                     1.6e-29, (31.1% identity in 482 aa overlap); and
                     Bacteriophage TP901-1. Protein product from Mb1612c
                     detected using SWATH mass spectrometry. Mb1612c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XZ46"
                     /db_xref="InterPro:IPR011109"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZ46"
BEGIN
        1 MATPQGRLVA RLKGSVAAHE TEHKKARQRR AARQKAERGH PNWSKAFGYL PGPNGPEPDP
       61 RTAPLVKQAY ADILAGASLG DVCRQWNDAG AFTITGRPWT TTTLSKFLRK PRNAGLRAYK
      121 GARYGPVDRD AIVGKAQWSP LVDEATFWAA QAVLDAPGRA PGRKSVRRHL LTGLAGCGKC
      181 GNHLAGSYRT DGQVVYVCKA CHGVAILADN IEPILYHIVA ERLAMPDAVD LLRREIHDAA
      241 EAETIRLELE TLYGELDRLA VERAEGLLTA RQVKISTDIV NAKITKLQAR QQDQERLRVF
      301 DGIPLGTPQV AGMIAELSPD RFRAVLDVLA EVVVQPVGKS GRIFNPERVQ VNWR
//