LOCUS       SIU00207.1               170 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            phiRv1 phage protein protein.
ACCESSION   LT708304-1620
PROTEIN_ID  SIU00207.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1603C"
                     /note="Mb1603c, -, len: 170 aa. Equivalent to Rv1577c,
                     len: 170 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 170 aa overlap). Probable phiRv1 phage
                     protein (prohead protease) (see citation below). Highly
                     similar to hypothetical protein Rv2651c|MTCY441.20c phiRV2
                     prohead protease, FASTA scores: E(): 0, (89.3% identity in
                     169 aa overlap). Some similarity to VP4_BPHK7|P49860
                     putative bacteriophage HK97 prohead protease (gp4) (225
                     aa), FASTA results: opt: 176, E(): 1.3e-05, (27.3%
                     identity in 165 aa overlap). Mb1603c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR006433"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYR4"
BEGIN
        1 MAELRSGEGR TVHGTIVPYN EATTVRDFDG EFQEMFAPGA FRRSIAERGH KLKLLVSHDA
       61 RTRYPVGRAV ELREEPHGLF GAFEIADTPD GDEALANVKA GVVDSFSVGF RPIRDRREGD
      121 VLVRVEAALL EVSLTGVPAY SGAQIAGVRA ESLTVVSRST AEAWLSLLDW
//