LOCUS       SIU00192.1               244 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Maltooligosyltreh
            alose synthase TreYb [SECOND PART] protein.
ACCESSION   LT708304-1605
PROTEIN_ID  SIU00192.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="treYb"
                     /locus_tag="BQ2027_MB1589C"
                     /standard_name="glgY"
                     /note="Mb1589c, treYb, len: 244 aa. Equivalent to the 3'
                     end of Rv1563c, len: 765 aa, from Mycobacterium
                     tuberculosis strain H37Rv, (100% identity in 244 aa
                     overlap). treY (previously called glgY), maltooligosyl
                     trehalose synthase, confirmed biochemically (see citation
                     below). Strong similarity to Q44315|63343 TREY
                     MALTOOLIGOSYL TREHALOSE SYNTHASE from ARTHROBACTER SP (775
                     aa), fasta scores: opt: 1953, E(): 0; (46.0% identity in
                     789 aa overlap). Some similarity to alpha-amylases and to
                     MTCY48.03 (30.2% identity in 215 aa overlap). May catalyse
                     conversion of maltodextrins to maltooligosyl trehaloses.
                     Also similar to Mycobacterium tuberculosis glgB (Rv1326c),
                     treZ (Rv1562c). REMARK-M.bovis-M.tuberculosis: In
                     Mycobacterium tuberculosis strain H37Rv, Rv1563c/treY
                     exists as a single gene. In Mycobacterium bovis, a large
                     deletion of 806 bp splits Rv1563c into two parts, treYa
                     and treYb. Protein product from Mb1589c detected using
                     SWATH mass spectrometry. Mb1589c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR017853"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYN8"
BEGIN
        1 MTGQFLWQNV FGVWPVSGEV SAALRGRLHT YAEKAIREAA WHTSWHNPNR AFEDDVHGWL
       61 DLVLDGPLAS ELTGLVAHLN SHAESDALAA KLLALTVPGV PDVYQGSELW DDSLVDPDNR
      121 RPVDYGTRRV ALKALQHPKI RVLAAALRLR RTHPESFLGG AYHPVFAAGP AADHVVAFRR
      181 GDDILVAVTR WTVRLQQTGW DHTVLPLPDG SWTDALTGFT ASGHTPAVEL FADLPVVLLV
      241 RDNA
//