LOCUS SIU00164.1 225 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable transcriptional regulator protein. ACCESSION LT708304-1577 PROTEIN_ID SIU00164.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1561" /note="Mb1561, -, len: 225 aa. Equivalent to Rv1534, len: 225 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 225 aa overlap). Probable transcriptional regulator, similar to YCDC_ECOLI|P75899 hypothetical transcriptional regulator from Escherichia coli (212 aa), FASTA scores: opt: 166, E(): 9.8e-05, (24.2% identity in 219 aa overlap). Contains PS01081 Bacterial regulatory proteins, tetR family signature and helix turn helix motif (aa 41-62). Protein product from Mb1561 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1561 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XZJ7" /db_xref="InterPro:IPR001647" /db_xref="InterPro:IPR009057" /db_xref="InterPro:IPR023772" /db_xref="InterPro:IPR036271" /db_xref="InterPro:IPR041669" /db_xref="UniProtKB/TrEMBL:A0A1R3XZJ7" BEGIN 1 MSRASARRRR AVSDEDKSQR RDEILAAAKI VFAHKGFHAT TVADIAKQAG LAYGLIYWYF 61 DSKDDLFHAL MAGEEEALRA HVAAELARVG GSTEAPLRAL LQAAVQATFE FFETDKATVK 121 LLFRDAYALG GRFEEHLGGI YERFIDDIEA VVVAAQRRGE VVEAPSRMAA YTLAALVGQL 181 AHRRLNTDDN VTAAQVADFV VSLVLDGLRP RALAVGARGG RAART //