LOCUS       SIU00164.1               225 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            transcriptional regulator protein.
ACCESSION   LT708304-1577
PROTEIN_ID  SIU00164.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1561"
                     /note="Mb1561, -, len: 225 aa. Equivalent to Rv1534, len:
                     225 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 225 aa overlap). Probable
                     transcriptional regulator, similar to YCDC_ECOLI|P75899
                     hypothetical transcriptional regulator from Escherichia
                     coli (212 aa), FASTA scores: opt: 166, E(): 9.8e-05,
                     (24.2% identity in 219 aa overlap). Contains PS01081
                     Bacterial regulatory proteins, tetR family signature and
                     helix turn helix motif (aa 41-62). Protein product from
                     Mb1561 detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb1561 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XZJ7"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR023772"
                     /db_xref="InterPro:IPR036271"
                     /db_xref="InterPro:IPR041669"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZJ7"
BEGIN
        1 MSRASARRRR AVSDEDKSQR RDEILAAAKI VFAHKGFHAT TVADIAKQAG LAYGLIYWYF
       61 DSKDDLFHAL MAGEEEALRA HVAAELARVG GSTEAPLRAL LQAAVQATFE FFETDKATVK
      121 LLFRDAYALG GRFEEHLGGI YERFIDDIEA VVVAAQRRGE VVEAPSRMAA YTLAALVGQL
      181 AHRRLNTDDN VTAAQVADFV VSLVLDGLRP RALAVGARGG RAART
//