LOCUS SIU00160.1 367 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable alcohol dehydrogenase adh protein. ACCESSION LT708304-1573 PROTEIN_ID SIU00160.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="adh" /locus_tag="BQ2027_MB1557" /note="Mb1557, adh, len: 367 aa. Equivalent to Rv1530, len: 367 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 367 aa overlap). Probable adh, alcohol dehydrogenase (EC 1.1.1.1), zinc-dependent, similar to many e.g. AE0009|AE000958_23 Archaeoglobus fulgidus section 1 (402 aa), FASTA scores: opt: 423, E(): 1.8e-19, (31.7% identity in 341 aa overlap). Contains PS00059 Zinc-containing alcohol dehydrogenases signature. Protein product from Mb1557 detected using SWATH mass spectrometry. Mb1557 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XYL6" /db_xref="InterPro:IPR002328" /db_xref="InterPro:IPR011032" /db_xref="InterPro:IPR013149" /db_xref="InterPro:IPR013154" /db_xref="InterPro:IPR036291" /db_xref="UniProtKB/TrEMBL:A0A1R3XYL6" BEGIN 1 MSDGAVVRAL VLEAPRRLVV RQYRLPRIGD DDALVRVEAC GLCGTDHEQY TGELAGGFAF 61 VPGHETVGTI AAIGPRAEQR WGVSAGDRVA VEVFQSCRQC ANCRGGEYRR CVRHGLADMY 121 GFIPVDREPG LWGGYAEYQY LAPDSMVLRV AGDLSPEVAT LFNPLGAGIR WGVTIPETKP 181 GDVVAVLGPG IRGLCAAAAA KGAGAGFVMV TGLGPRDADR LALAAQFGAD LAVDVAIDDP 241 VAALTEQTGG LADVVVDVTA KAPAAFAQAI ALARPAGTVV VAGTRGVGSG APGFSPDVVV 301 FKELRVLGAL GVDATAYRAA LDLLVSGRYP FASLPRRCVR LEGAEDLLAT MAGERDGVPP 361 IHGVLTP //