LOCUS       SIU00153.1               347 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Probable
            methyltransferase protein.
ACCESSION   LT708304-1566
PROTEIN_ID  SIU00153.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1550"
                     /note="Mb1550, -, len: 347 aa. Equivalent to Rv1523, len:
                     347 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 347 aa overlap). Probable
                     methyltransferase (EC 2.1.1.-), similar to G560513|U0002O
                     Mycobacterium leprae (270 aa), FASTA scores: opt: 965,
                     E(): 0, (60.3% identity in 247 aa overlap). Also similar
                     to many e.g. Q54303|X86780 METHYLTRANSFERASE RAPM from
                     Streptomyces hygroscopicus (317 aa), FASTA scores: opt:
                     323, E(): 1e-15, (41.2% identity in 136 aa overlap). And
                     similar to Mycobacterium tuberculosis hypothetical
                     proteins Rv2952, Rv1405c, Rv1403c, Rv0839. Start
                     uncertain. Protein product from Mb1550 detected using
                     SWATH mass spectrometry. Mb1550 found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y0R2"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y0R2"
BEGIN
        1 MTITALTVTL PLLWRRLTTA GVKYADQGHF VGSAGVPAAD AGGRDAASEQ IARWTQTCTV
       61 VLVCGHGPAK WAFRSWCTSR SCDTLPVALR YRLQSNPLVG KLTTKYFLPL GTRQVGDHVV
      121 FFNFGYEEDP PMALPLSESD EPNRYCIQLY HQTASQVDLT GKEVLEVSCG AGGGASYIAR
      181 NLGPASYTGL DLNPASIDLC RAKHRLPGLQ FVQGDAQNLP FPDESFDAVV NVEASHQYPD
      241 FRGFLAEVAR VLRPGGHFLY TDSRRNPVVA EWEAALADAP LRTISQRDIG AQAKRGLDAN
      301 TARSQEAIGR RAPVLLAGLT RCAVRVLDWD LRRGGGFSYR IYLFAKD
//