LOCUS SIU00153.1 347 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable methyltransferase protein. ACCESSION LT708304-1566 PROTEIN_ID SIU00153.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1550" /note="Mb1550, -, len: 347 aa. Equivalent to Rv1523, len: 347 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 347 aa overlap). Probable methyltransferase (EC 2.1.1.-), similar to G560513|U0002O Mycobacterium leprae (270 aa), FASTA scores: opt: 965, E(): 0, (60.3% identity in 247 aa overlap). Also similar to many e.g. Q54303|X86780 METHYLTRANSFERASE RAPM from Streptomyces hygroscopicus (317 aa), FASTA scores: opt: 323, E(): 1e-15, (41.2% identity in 136 aa overlap). And similar to Mycobacterium tuberculosis hypothetical proteins Rv2952, Rv1405c, Rv1403c, Rv0839. Start uncertain. Protein product from Mb1550 detected using SWATH mass spectrometry. Mb1550 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y0R2" /db_xref="InterPro:IPR013216" /db_xref="InterPro:IPR029063" /db_xref="UniProtKB/TrEMBL:A0A1R3Y0R2" BEGIN 1 MTITALTVTL PLLWRRLTTA GVKYADQGHF VGSAGVPAAD AGGRDAASEQ IARWTQTCTV 61 VLVCGHGPAK WAFRSWCTSR SCDTLPVALR YRLQSNPLVG KLTTKYFLPL GTRQVGDHVV 121 FFNFGYEEDP PMALPLSESD EPNRYCIQLY HQTASQVDLT GKEVLEVSCG AGGGASYIAR 181 NLGPASYTGL DLNPASIDLC RAKHRLPGLQ FVQGDAQNLP FPDESFDAVV NVEASHQYPD 241 FRGFLAEVAR VLRPGGHFLY TDSRRNPVVA EWEAALADAP LRTISQRDIG AQAKRGLDAN 301 TARSQEAIGR RAPVLLAGLT RCAVRVLDWD LRRGGGFSYR IYLFAKD //