LOCUS       SIU00138.1               257 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            METHYLTRANSFERASE protein.
ACCESSION   LT708304-1551
PROTEIN_ID  SIU00138.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1535C"
                     /note="Mb1535c, -, len: 205 aa. Equivalent to Rv1498c,
                     len: 205 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.5% identity in 205 aa overlap). Probable
                     methyltransferase (EC 2.1.1.-). Similar to
                     G2792343|AF040571 METHYLTRANSFERASE from AMYCOLATOPSIS
                     MEDITERRANEI (272 aa), FASTA scores: E(): 5.1e-11, (32.3%
                     identity in 124 aa overlap). Contains PS00017
                     ATP/GTP-binding site motif A. Protein product from Mb1535c
                     detected using SWATH mass spectrometry. Mb1535c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XYJ0"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYJ0"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTRSKRGSAD GGSAEALPPK SLRQFVGGAY KEVGAEFVGY LVDLCGLQPD EAVLDVGCGS
       61 GRMALPLTGY LNSEGRYAGF DISQKAIAWC QEHITSAHPN FQFEVSDIYN SLYNPKGKYQ
      121 SLDFRFPYPD ASFDVVFLTS VFTHMFPPDV EHYLDEISRV LKPGGRCLCT YFLLNDESLA
      181 HIAEGKSAHN FQHEGPGYRT IHKKRPEEAI GLPETFVRDV YGKFGLAVHE PLHYGSWSGR
      241 EPHLSFQDIV IATKTAS
//