LOCUS SIU00138.1 257 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE METHYLTRANSFERASE protein. ACCESSION LT708304-1551 PROTEIN_ID SIU00138.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1535C" /note="Mb1535c, -, len: 205 aa. Equivalent to Rv1498c, len: 205 aa, from Mycobacterium tuberculosis strain H37Rv, (99.5% identity in 205 aa overlap). Probable methyltransferase (EC 2.1.1.-). Similar to G2792343|AF040571 METHYLTRANSFERASE from AMYCOLATOPSIS MEDITERRANEI (272 aa), FASTA scores: E(): 5.1e-11, (32.3% identity in 124 aa overlap). Contains PS00017 ATP/GTP-binding site motif A. Protein product from Mb1535c detected using SWATH mass spectrometry. Mb1535c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XYJ0" /db_xref="InterPro:IPR013216" /db_xref="InterPro:IPR029063" /db_xref="UniProtKB/TrEMBL:A0A1R3XYJ0" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MTRSKRGSAD GGSAEALPPK SLRQFVGGAY KEVGAEFVGY LVDLCGLQPD EAVLDVGCGS 61 GRMALPLTGY LNSEGRYAGF DISQKAIAWC QEHITSAHPN FQFEVSDIYN SLYNPKGKYQ 121 SLDFRFPYPD ASFDVVFLTS VFTHMFPPDV EHYLDEISRV LKPGGRCLCT YFLLNDESLA 181 HIAEGKSAHN FQHEGPGYRT IHKKRPEEAI GLPETFVRDV YGKFGLAVHE PLHYGSWSGR 241 EPHLSFQDIV IATKTAS //