LOCUS SIU00131.1 252 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED MEMBRANE PROTEIN protein. ACCESSION LT708304-1544 PROTEIN_ID SIU00131.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1528C" /note="Mb1528c, -, len: 252 aa. Equivalent to Rv1491c, len: 252 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 252 aa overlap). Conserved membrane protein. Similar to hypothetical proteins from many organisms e.g. YDJZ_ECOLI|P76221 Escherichia coli (235 aa), FASTA scores: opt: 223, E():6.7e-07, (31.7% identity in 145 aa overlap); AL133252|SCE46.15 Streptomyces coelicolor (249 aa), FASTA scores: opt: 378, E(): 1.5e-17, (39.1% identity in 169 aa overlap). Also similar to M. tuberculosis hypothetical protein Rv0625c. Mb1528c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:P67118" /db_xref="InterPro:IPR015414" /db_xref="InterPro:IPR032816" /db_xref="UniProtKB/Swiss-Prot:P67118" BEGIN 1 MTAPAICNTT ETVHGIATSL GAVARQASLP RIVGTVVGIT VLVVVALLVP VPTAVELRDW 61 AKSLGAWFPL AFLLVHTVVT VPPFPRTAFT LAAGLLFGSV VGVFIAVVGS TASAVIAMLL 121 VRATGWQLNS LVRRRAINRL DERLRERGWL AILSLRLIPV VPFAAINYAA GASGVRILSF 181 AWATLAGLLP GTAAVVILGD AFAGSGSPLL ILVSVCTGAL GLTGLVYEIR NYRRQHRRMP 241 GYDDPVREPA LI //