LOCUS       SIU00131.1               252 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED
            MEMBRANE PROTEIN protein.
ACCESSION   LT708304-1544
PROTEIN_ID  SIU00131.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1528C"
                     /note="Mb1528c, -, len: 252 aa. Equivalent to Rv1491c,
                     len: 252 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 252 aa overlap). Conserved membrane
                     protein. Similar to hypothetical proteins from many
                     organisms e.g. YDJZ_ECOLI|P76221 Escherichia coli (235
                     aa), FASTA scores: opt: 223, E():6.7e-07, (31.7% identity
                     in 145 aa overlap); AL133252|SCE46.15 Streptomyces
                     coelicolor (249 aa), FASTA scores: opt: 378, E(): 1.5e-17,
                     (39.1% identity in 169 aa overlap). Also similar to M.
                     tuberculosis hypothetical protein Rv0625c. Mb1528c found
                     to be expressed during exponential growth in Sauton's
                     minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:P67118"
                     /db_xref="InterPro:IPR015414"
                     /db_xref="InterPro:IPR032816"
                     /db_xref="UniProtKB/Swiss-Prot:P67118"
BEGIN
        1 MTAPAICNTT ETVHGIATSL GAVARQASLP RIVGTVVGIT VLVVVALLVP VPTAVELRDW
       61 AKSLGAWFPL AFLLVHTVVT VPPFPRTAFT LAAGLLFGSV VGVFIAVVGS TASAVIAMLL
      121 VRATGWQLNS LVRRRAINRL DERLRERGWL AILSLRLIPV VPFAAINYAA GASGVRILSF
      181 AWATLAGLLP GTAAVVILGD AFAGSGSPLL ILVSVCTGAL GLTGLVYEIR NYRRQHRRMP
      241 GYDDPVREPA LI
//