LOCUS       SIU00128.1               118 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 conserved
            protein protein.
ACCESSION   LT708304-1541
PROTEIN_ID  SIU00128.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1525"
                     /note="Mb1525, -, len: 118 aa. Equivalent to Rv1489, len:
                     118 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 118 aa overlap). Conserved hypothetical
                     protein, similar to hypothetical proteins from
                     Mycobacterium avium subsp. paratuberculosis and
                     Streptomyces coelicolor e.g. AJ250017_1 insertion sequence
                     IS900, Locus 3, putative invasion protein from M.
                     paratuberculosis (138 aa), FASTA scores: opt: 120, E():
                     0.26, (34.375% identity in 96 aa overlap);
                     SCD6.11c|AL353815_11 possible integral membrane protein
                     from Streptomyces coelicolor (136 aa), FASTA scores: opt:
                     106, E(): 2.2, (35.9% identity in 103 aa overlap). ORF
                     predicted by GC plot. Replaces previous Rv1489c on other
                     strand. Protein product from Mb1525 detected using shotgun
                     mass spectrometry. Mb1525 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XYI2"
                     /db_xref="InterPro:IPR032808"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYI2"
BEGIN
        1 MSGLTSPKTY AVLAALQAGD AVACAIPLPP IARLLDDLDV PVSVRPVLPV VKAASAVGLL
       61 SVTRFPALAR LTTAMLTLYF ILAVGAHVRV RDRVVNAIPA ASFLTLFALM TAKGPERT
//