LOCUS       SIU00126.1               144 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED
            MEMBRANE PROTEIN protein.
ACCESSION   LT708304-1539
PROTEIN_ID  SIU00126.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1523"
                     /note="Mb1523, -, len: 144 aa. Equivalent to Rv1487, len:
                     144 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 144 aa overlap). Conserved membrane
                     protein. Highly similar to O07404|AF002133 MAV145 from
                     Mycobacterium avium (145 aa), FASTA scores: opt: 667, E():
                     0, (72.5% identity in 142 aa overlap). Also similar to
                     AL079332|SCI5.05 hypothetical protein from Streptomyces
                     coelicolor (143 aa), FASTA scores: opt: 344, E(): 1.3e-15,
                     (44.8% identity in 134 aa overlap). Protein product from
                     Mb1523 detected using SWATH mass spectrometry. Mb1523
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3XYW5"
                     /db_xref="InterPro:IPR002810"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYW5"
BEGIN
        1 MPVALIWLIA ALVLVGAEAL TGDMFLLMLG GGALAASVSS WLLAWPMWAD GAVFLLVSVL
       61 LLVLVRPAVR RRLTQTKGVQ LGIEALEGKK AVVLGRVARD GGQVKLDGQV WTARPLNDGD
      121 VFEPGDSVTV VQIDGATAVV FKDV
//