LOCUS SIU00125.1 288 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED HYPOTHETICAL PROTEIN protein. ACCESSION LT708304-1538 PROTEIN_ID SIU00125.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1522C" /note="Mb1522c, -, len: 288 aa. Equivalent to Rv1486c, len: 288 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 288 aa overlap). Conserved hypothetical protein, highly similar to YS07_MYCAV|O07402 hypothetical 33.5 kd protein mav321 from Mycobacterium avium (320 aa), FASTA scores: opt: 1217, E(): 0, (71.1% identity in 315 aa overlap). Weak similarity to AL079332|SCI5.07 hypothetical protein from Streptomyces coelicolor (259 aa), FASTA scores: opt: 131, E(): 0.29, (32.3% identity in 279 aa overlap). Start changed since original submission. Protein product from Mb1522c detected using SWATH mass spectrometry. Mb1522c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="UniProtKB/Swiss-Prot:P59980" BEGIN 1 MWCPSVSLSI WANAWLAGKA APDDVLDALS LWAPTQSVAA YDAVAAGHTG LPWPDVHDAG 61 TVSLLQTLRA AVGRRRLRGT INVVLPVPGD VRGLAAGTQF EHDALAAGEA VIVANPEDPG 121 SAVGLVPEFS YGDVDEAAQS EPLTPELCAL SWMVYSLPGA PVLEHYELGD AEYALRSAVR 181 SAAEALSTIG LGSSDVANPR GLVEQLLESS RQHRVPDHAP SRALRVLENA AHVDAIIAVS 241 AGLSRLPIGT QSLSDAQRAT DALRPLTAVV RSARMSAVTA ILHSAWPD //