LOCUS SIU00119.1 317 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 conserved protein protein. ACCESSION LT708304-1532 PROTEIN_ID SIU00119.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1516" /note="Mb1516, -, len: 317 aa. Equivalent to Rv1480, len: 317 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 317 aa overlap). Conserved hypothetical protein, last 110 aa residues correspond to first 110 aa of YS01_MYCAV|O07394 hypothetical 18.7 KD Mycobacterium avium protein MAV169 (169 aa), FASTA scores: opt: 642, E(): 0, (84.2% identity in 114 aa overlap). Also similar to Mycobacterium tuberculosis hypothetical proteins Rv3163c and Rv3693. Protein product from Mb1516 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1516 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR002881" /db_xref="InterPro:IPR036465" /db_xref="UniProtKB/Swiss-Prot:P64854" BEGIN 1 MTESKAPAVV HPPSMLRGDI DDPKLAAALR TLELTVKQKL DGVLHGDHLG LIPGPGSEPG 61 ESRLYQPGDD VRRMDWAVTA RTTHPHVRQM IADRELETWL VVDMSASLDF GTACCEKRDL 121 AVAAAAAITF LNSGGGNRLG ALIANGAAMT RVPARTGRQH QHTMLRTIAT MPQAPAGVRG 181 DLAVAIDALR RPERRRGMAV IISDFLGPIN WMRPLRAIAA RHEVLAIEVL DPRDVELPDV 241 GDVVLQDAES GVVREFSIDP ALRDDFARAA AAHRADVART IRGCGAPLLS LRTDRDWLAD 301 IVRFVASRRR GALAGHQ //