LOCUS SIU00108.1 124 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE THIOREDOXIN TRXA protein. ACCESSION LT708304-1521 PROTEIN_ID SIU00108.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="trxA" /locus_tag="BQ2027_MB1505" /note="Mb1505, trxA, len: 124 aa. Equivalent to Rv1470, len: 124 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 124 aa overlap). Probable trxA, thioredoxin (EC 1.-.-.-), similar to many e.g. P12243|THI1_SYNP7 THIOREDOXIN 1 from Synechococcus sp. (106 aa), FASTA scores: opt: 201, E(): 9.2e-08, (35.4% identity in 99 aa overlap); etc. Highly similar to downstream ORF Rv1471|trxB1 probable thioredoxin from M. tuberculosis (123 aa), FASTA scores: opt: 402, E(): 0, (54.4% identity in 114 aa overlap). Warning: note that Rv3914|MT4033|MTV028.05|trxC can be alternatively named trxA. Protein product from Mb1505 detected using SWATH mass spectrometry. Mb1505 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XYG2" /db_xref="InterPro:IPR013766" /db_xref="InterPro:IPR036249" /db_xref="UniProtKB/TrEMBL:A0A1R3XYG2" BEGIN 1 MTTRDLTAAY FQQTISANSN VLVYFWAPLC APCDLFTPTY EASSRKHFDV VHGKVNIETE 61 KDLASIAGVK LLPTLMAFKK GKLVFKQAGI ANPAIMDNLV QQLRAYTFKS PAGEGIGPGT 121 KTSS //