LOCUS       SIU00108.1               124 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            THIOREDOXIN TRXA protein.
ACCESSION   LT708304-1521
PROTEIN_ID  SIU00108.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="trxA"
                     /locus_tag="BQ2027_MB1505"
                     /note="Mb1505, trxA, len: 124 aa. Equivalent to Rv1470,
                     len: 124 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 124 aa overlap). Probable trxA,
                     thioredoxin (EC 1.-.-.-), similar to many e.g.
                     P12243|THI1_SYNP7 THIOREDOXIN 1 from Synechococcus sp.
                     (106 aa), FASTA scores: opt: 201, E(): 9.2e-08, (35.4%
                     identity in 99 aa overlap); etc. Highly similar to
                     downstream ORF Rv1471|trxB1 probable thioredoxin from M.
                     tuberculosis (123 aa), FASTA scores: opt: 402, E(): 0,
                     (54.4% identity in 114 aa overlap). Warning: note that
                     Rv3914|MT4033|MTV028.05|trxC can be alternatively named
                     trxA. Protein product from Mb1505 detected using SWATH
                     mass spectrometry. Mb1505 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3XYG2"
                     /db_xref="InterPro:IPR013766"
                     /db_xref="InterPro:IPR036249"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYG2"
BEGIN
        1 MTTRDLTAAY FQQTISANSN VLVYFWAPLC APCDLFTPTY EASSRKHFDV VHGKVNIETE
       61 KDLASIAGVK LLPTLMAFKK GKLVFKQAGI ANPAIMDNLV QQLRAYTFKS PAGEGIGPGT
      121 KTSS
//