LOCUS       SIU00099.1               846 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Iron-
            sulfur cluster assembly protein SufB protein.
ACCESSION   LT708304-1512
PROTEIN_ID  SIU00099.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1496"
                     /note="Mb1496, -, len: 846 aa. Equivalent to Rv1461, len:
                     846 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 846 aa overlap). Conserved hypothetical
                     protein. Equivalent of spliced protein from Mycobacterium
                     leprae MLCL536.28c len: 869. Residues 1-253 represent
                     N-extein, and 613-846 the C-extein. The intein present
                     from residues 254 - 612 is different in sequence and site
                     of the insertion from the one present in MLCL536.28c.
                     FASTA scores: Z99125|MLCL536_23 Mycobacterium leprae
                     cosmid L536 (869 aa), opt: 1498 E(): 0, (54.1% identity in
                     917 aa overlap). The mature protein is similar to
                     Z99120|BSUB0017_150 hypothetical Bacillus subtilis protein
                     (465 aa), FASTA scores: opt:1053, E(): 0, (34.8% identity
                     in 821 aa overlap). The intein shows some similarity to
                     inteins from U67548|MJU67548_6 Methanococcus jannaschii
                     (895 aa), FASTA scores: opt: 181, E(): 0.00023, (25.2%
                     identity in 274 aa overlap). Protein product from Mb1496
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb1496 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P67126"
                     /db_xref="InterPro:IPR000825"
                     /db_xref="InterPro:IPR003586"
                     /db_xref="InterPro:IPR003587"
                     /db_xref="InterPro:IPR004042"
                     /db_xref="InterPro:IPR006141"
                     /db_xref="InterPro:IPR006142"
                     /db_xref="InterPro:IPR010231"
                     /db_xref="InterPro:IPR027434"
                     /db_xref="InterPro:IPR030934"
                     /db_xref="InterPro:IPR036844"
                     /db_xref="InterPro:IPR037284"
                     /db_xref="UniProtKB/Swiss-Prot:P67126"
BEGIN
        1 MTLTPEASKS VAQPPTQAPL TQEEAIASLG RYGYGWADSD VAGANAQRGL SEAVVRDISA
       61 KKNEPDWMLQ SRLKALRIFD RKPIPKWGSN LDGIDFDNIK YFVRSTEKQA ASWDDLPEDI
      121 RNTYDRLGIP EAEKQRLVAG VAAQYESEVV YHQIREDLEA QGVIFLDTDT GLREHPDIFK
      181 EYFGTVIPAG DNKFSALNTA VWSGGSFIYV PPGVHVDIPL QAYFRINTEN MGQFERTLII
      241 ADEGSYVHYV EGCLPAGELI TTADGDLRPI ESIRVGDFVT GHDGRPHRVT AVQVRDLDGE
      301 LFTFTPMSPA NAFSVTAEHP LLAIPRDEVR VMRKERNGWK AEVNSTKLRS AEPRWIAAKD
      361 VAEGDFLIYP KPKPIPHRTV LPLEFARLAG YYLAEGHACL TNGCESLIFS FHSDEFEYVE
      421 DVRQACKSLY EKSGSVLIEE HKHSARVTVY TKAGYAAMRD NVGIGSSNKK LSDLLMRQDE
      481 TFLRELVDAY VNGDGNVTRR NGAVWKRVHT TSRLWAFQLQ SILARLGHYA TVELRRPGGP
      541 GVIMGRNVVR KDIYQVQWTE GGRGPKQARD CGDYFAVPIK KRAVREAHEP VYNLDVENPD
      601 SYLAYGFAVH NCTAPIYKSD SLHSAVVEII VKPHARVRYT TIQNWSNNVY NLVTKRARAE
      661 AGATMEWIDG NIGSKVTMKY PAVWMTGEHA KGEVLSVAFA GEDQHQDTGA KMLHLAPNTS
      721 SNIVSKSVAR GGGRTSYRGL VQVNKGAHGS RSSVKCDALL VDTVSRSDTY PYVDIREDDV
      781 TMGHEATVSK VSENQLFYLM SRGLTEDEAM AMVVRGFVEP IAKELPMEYA LELNRLIELQ
      841 MEGAVG
//