LOCUS SIU00098.1 268 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN protein. ACCESSION LT708304-1511 PROTEIN_ID SIU00098.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1495" /note="Mb1495, -, len: 268 aa. Equivalent to Rv1460, len: 268 aa, from Mycobacterium tuberculosis strain H37Rv, (99.6% identity in 268 aa overlap). Probable transcriptional regulatory protein. Equivalent to Z99125|MLCL536.29c hypothetical protein from Mycobacterium leprae (254 aa), FASTA scores: opt: 1273, E(): 0, (79.6% identity in 250 aa overlap). Possible helix-turn-helix motif between aa 68 - 89. Start changed since original submission. Protein product from Mb1495 detected using SWATH mass spectrometry. Mb1495 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR011991" /db_xref="InterPro:IPR036388" /db_xref="InterPro:IPR036390" /db_xref="UniProtKB/TrEMBL:A0A1R3XYF5" BEGIN 1 MTSTTLPHRA SLVDRSTEFC HTDVVKIPAV STTVPAAVSD GHTRRAIVRL LLESGSITAG 61 EIGDRLGLSA AGVRRHLDAL IEAGDAEASA AAPWQQVGRG RPAKRYRLTA AGRAKLDHSY 121 DDLASAAMRQ LREIGGEEAV RTFARRRIDA ILADVAPADG PDDAALEAAA ERIATALSKA 181 GYVATTTRVG GPIHGVQICQ HHCPVSHVAE EFPELCETEQ QAMAEVLGTH VQRLATIVNG 241 DCACTTHVPL SPAPSPRPPA TSTEGVSR //