LOCUS SIU00096.1 313 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE UNIDENTIFIED ANTIBIOTIC-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER protein. ACCESSION LT708304-1509 PROTEIN_ID SIU00096.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1493C" /note="Mb1493c, -, len: 313 aa. Equivalent to Rv1458c, len: 313 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 313 aa overlap). Possible unidentified antibiotic-transport ATP-binding protein ABC transporter (see citation below), equivalent to Z99125|MLCL536.31 from Mycobacterium leprae (315 aa), FASTA scores: opt: 1812, E(): 0, (88.0% identity in 308 aa overlap). Similar to AF027770|AF027770_7 ABC-type transporter in FxbA region in Mycobacterium smegmatis (284 aa), FASTA scores: opt: 1412, E(): 0, (85.1% identity in 248 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop) and PS00211 ABC transporters family signature. BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS). Protein product from Mb1493c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb1493c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XYT3" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="UniProtKB/TrEMBL:A0A1R3XYT3" BEGIN 1 MNRAPDTPEV VLRLRGVCKR YGSITAVSNL DLDVHDAEVM ALLGPNGAGK TTTVEMCEGF 61 VRPDAGSIEV LGLDPITDNA RLRARIGVML QGGGGYPAAR AGEMLDLVAS YAANPLDPHW 121 LLDTLGLTEA ARTTYRRLSG GQQQRLALAC ALVGRPQLVF LDEPTAGMDA HARVLVWELI 181 DALRRDGVTV VLTTHHLKEA EELADRLVII DHGVTVAAGT PAELMRSGAK DQLRFTAPPR 241 LDLSLLASAL PEGYQATELT PGEYLVEGPV DPQVLATVTA WCAQIDVLAT DMRVEQRSLE 301 DVFLDLTGRK LRQ //