LOCUS       SIU00096.1               313 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            UNIDENTIFIED ANTIBIOTIC-TRANSPORT ATP-BINDING PROTEIN
            ABC TRANSPORTER protein.
ACCESSION   LT708304-1509
PROTEIN_ID  SIU00096.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1493C"
                     /note="Mb1493c, -, len: 313 aa. Equivalent to Rv1458c,
                     len: 313 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 313 aa overlap). Possible unidentified
                     antibiotic-transport ATP-binding protein ABC transporter
                     (see citation below), equivalent to Z99125|MLCL536.31 from
                     Mycobacterium leprae (315 aa), FASTA scores: opt: 1812,
                     E(): 0, (88.0% identity in 308 aa overlap). Similar to
                     AF027770|AF027770_7 ABC-type transporter in FxbA region in
                     Mycobacterium smegmatis (284 aa), FASTA scores: opt: 1412,
                     E(): 0, (85.1% identity in 248 aa overlap). Contains
                     PS00017 ATP/GTP-binding site motif A (P-loop) and PS00211
                     ABC transporters family signature. BELONGS TO THE
                     ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS).
                     Protein product from Mb1493c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1493c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XYT3"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYT3"
BEGIN
        1 MNRAPDTPEV VLRLRGVCKR YGSITAVSNL DLDVHDAEVM ALLGPNGAGK TTTVEMCEGF
       61 VRPDAGSIEV LGLDPITDNA RLRARIGVML QGGGGYPAAR AGEMLDLVAS YAANPLDPHW
      121 LLDTLGLTEA ARTTYRRLSG GQQQRLALAC ALVGRPQLVF LDEPTAGMDA HARVLVWELI
      181 DALRRDGVTV VLTTHHLKEA EELADRLVII DHGVTVAAGT PAELMRSGAK DQLRFTAPPR
      241 LDLSLLASAL PEGYQATELT PGEYLVEGPV DPQVLATVTA WCAQIDVLAT DMRVEQRSLE
      301 DVFLDLTGRK LRQ
//