LOCUS SIU00092.1 328 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE QUINONE REDUCTASE QOR (NADPH:quinone reductase) (Zeta- crystallin homolog protein) protein. ACCESSION LT708304-1505 PROTEIN_ID SIU00092.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="qor" /locus_tag="BQ2027_MB1489C" /note="Mb1489c, qor, len: 328 aa. Equivalent to Rv1454c, len: 328 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 328 aa overlap). Probable qor, quinone oxidoreductase (EC 1.6.5.5), simiar to U87282|RCU87282_2 quinone oxidoreductase from Rhodobacter capsulatus (323 aa), FASTA scores: opt: 849, E(): 0, (44.7% identity in 329 aa overlap). Also similar to MTCY180.06 Hypothetical protein from Mycobacterium tuberculosis (334 aa), FASTA scores: opt: 430, E(): 2e-14, (32.3% identity in 350 aa overlap). Contains PS01162 Quinone oxidoreductase / zeta-crystallin signature. Protein product from Mb1489c detected using shotgun mass spectrometry. Mb1489c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:A0A1R3XYD6" /db_xref="InterPro:IPR011032" /db_xref="InterPro:IPR013149" /db_xref="InterPro:IPR013154" /db_xref="InterPro:IPR020843" /db_xref="InterPro:IPR036291" /db_xref="UniProtKB/TrEMBL:A0A1R3XYD6" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MHAIEVTETG GPGVLRHVDQ PQPQPGHGEL LIKAEAIGVN FIDTYFRSGQ YPRELPFVIG 61 SEVCGTVEAV GPGVTAADTA ISVGDRVVSA SANGAYAEFC TAPASLTAKV PDDVTSEVAA 121 SALLKGLTAH YLLKSVYPVK RGDTVLVHAG AGGVGLILTQ WATHLGVRVI TTVSTAEKAK 181 LSKDAGADVV LDYPEDAWQF AGRVRELTGG TGVQAVYDGV GATTFDASLA SLAVRGTLAL 241 FGAASGPVPP VDPQRLNAAG SVYLTRPSLF HFTRTGEEFS WRAAELFDAI GSEAITVAVG 301 GRYPLADALR AHQDLEARKT VGSVVLLP //