LOCUS       SIU00092.1               328 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            QUINONE REDUCTASE QOR (NADPH:quinone reductase) (Zeta-
            crystallin homolog protein) protein.
ACCESSION   LT708304-1505
PROTEIN_ID  SIU00092.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="qor"
                     /locus_tag="BQ2027_MB1489C"
                     /note="Mb1489c, qor, len: 328 aa. Equivalent to Rv1454c,
                     len: 328 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 328 aa overlap). Probable qor, quinone
                     oxidoreductase (EC 1.6.5.5), simiar to U87282|RCU87282_2
                     quinone oxidoreductase from Rhodobacter capsulatus (323
                     aa), FASTA scores: opt: 849, E(): 0, (44.7% identity in
                     329 aa overlap). Also similar to MTCY180.06 Hypothetical
                     protein from Mycobacterium tuberculosis (334 aa), FASTA
                     scores: opt: 430, E(): 2e-14, (32.3% identity in 350 aa
                     overlap). Contains PS01162 Quinone oxidoreductase /
                     zeta-crystallin signature. Protein product from Mb1489c
                     detected using shotgun mass spectrometry. Mb1489c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3XYD6"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="InterPro:IPR020843"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYD6"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MHAIEVTETG GPGVLRHVDQ PQPQPGHGEL LIKAEAIGVN FIDTYFRSGQ YPRELPFVIG
       61 SEVCGTVEAV GPGVTAADTA ISVGDRVVSA SANGAYAEFC TAPASLTAKV PDDVTSEVAA
      121 SALLKGLTAH YLLKSVYPVK RGDTVLVHAG AGGVGLILTQ WATHLGVRVI TTVSTAEKAK
      181 LSKDAGADVV LDYPEDAWQF AGRVRELTGG TGVQAVYDGV GATTFDASLA SLAVRGTLAL
      241 FGAASGPVPP VDPQRLNAAG SVYLTRPSLF HFTRTGEEFS WRAAELFDAI GSEAITVAVG
      301 GRYPLADALR AHQDLEARKT VGSVVLLP
//