LOCUS SIU00079.1 491 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 pe- pgrs family protein pe_pgrs26 protein. ACCESSION LT708304-1492 PROTEIN_ID SIU00079.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="PE_PGRS26" /locus_tag="BQ2027_MB1476C" /note="Mb1476c, PE_PGRS26, len: 491 aa. Equivalent to Rv1441c, len: 491 aa, from Mycobacterium tuberculosis strain H37Rv, (99.6% identity in 491 aa overlap). Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins, similar to Y0DP_MYCTU|Q50615 hypothetical glycine-rich 40.8 kd protein (498 aa), fasta scores: opt: 1625, E(): 0, (55.2% identity in 518 aa overlap). Mb1476c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR000084" /db_xref="UniProtKB/TrEMBL:A0A1R3XYC1" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MSNVMVVPGM LSAAAADVAS IGAALSAANG AAAPTTAGVL AAGADEVSAA IASLFSGYAR 61 DYQALSAQMA RFHQQFVQAL TASVGSYAAA EAANASPLQA LEQQVLAAIN APTQTLLGRP 121 LIGNGADGLP GQNGGAGGLL WGNGGNGGAG DAAHPNGGNG GDAGMFGNGG AGGAGYSPAA 181 GTGAAGGAGG AGGAGGWLSG NGGAGGNGGT GASGADGGGG LPPVPASPGG NGGGGGAGGA 241 AGMFGTGGAG GTGGDGGAGG AGDSPNSGAN GARGGDGGNG AAGGAGGRLF GNGGAGGNGG 301 TAGQGGDGGT ALGAGGIGGD GGTGGAGGTG GTAGIGGSSA GAGGAGGDGG AGGNGGGSSM 361 IGGKGGTGGN GGVGGTGGAS ALTIGNGSSA GAGGAGGAGG TGGTGGYIES LDGKGQAGNG 421 GNGGNGAAGG AGGGGTGAGG NGGAGGNGGD GGPSQGGGNP GFGGDGGTGG PGGVGVPDGI 481 GGANGAQGKH G //