LOCUS SIU00071.1 271 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE CONSERVED EXPORTED PROTEIN protein. ACCESSION LT708304-1484 PROTEIN_ID SIU00071.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1468" /note="Mb1468, -, len: 271 aa. Equivalent to Rv1433, len: 271 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 271 aa overlap). Possible exported protein with N-terminal signal sequence, highly similar to Q49706 hypothetical protein from Mycobacterium leprae (271 aa), FASTA scores: opt: 1341, E(): 0, (68.3% identity in 271 aa overlap). Also shows similarity to Mycobacterium tuberculosis lipoprotein Rv2518c|MTV009.03c lppS (408 aa) (40.0% identity in 230 aa overlap); and others e.g. Rv0116c, Rv0192, Rv2518c, Rv0483. Mb1468 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3XYB7" /db_xref="InterPro:IPR005490" /db_xref="InterPro:IPR038063" /db_xref="InterPro:IPR041280" /db_xref="UniProtKB/TrEMBL:A0A1R3XYB7" BEGIN 1 MRAVFGCAIA VVGIAGSVVA GPADIHLVAA KQSYGFAVAS VLPTRGQVVG VAHPVVVTFS 61 APITNPANRH AAERAVEVKS TPAMTGKFEW LDNDVVQWVP DRFWPAHSTV ELSVGSLSSD 121 FKTGPAVVGV ASISQHTFTV SIDGVEEGPP PPLPAPHHRV HFGEDGVMPA SMGRPEYPTP 181 VGSYTVLSKE RSVIMDSSSV GIPVDDPDGY RLSVDYAVRI TSRGLYVHSA PWALPALGLE 241 NVSHGCISLS REDAEWYYNA VDIGDPVIVQ E //