LOCUS       SIU00067.1               422 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Possible
            regulatory protein Trx protein.
ACCESSION   LT708304-1480
PROTEIN_ID  SIU00067.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1464"
                     /note="Mb1464, -, len: 422 aa. Equivalent to Rv1429, len:
                     422 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 422 aa overlap). Conserved hypothetical
                     protein, some similarity to transcriptional regulator
                     proteins e.g. CDAR_ECOLI|P37047 Carbohydrate diacid
                     regulator from Escherichia coli (391 aa), FASTA scores:
                     opt: 210, E(): 3e-06, (27.7% identity in 296 aa overlap).
                     Also similar to Mycobacterium tuberculosis hypothetical
                     proteins Rv2370c, Rv1194c, Rv1453, Rv2242, and Rv1186c.
                     Protein product from Mb1464 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1464 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="InterPro:IPR025736"
                     /db_xref="InterPro:IPR041522"
                     /db_xref="InterPro:IPR042070"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XYC5"
BEGIN
        1 MAEAGGGPIS VIARHMQLIR DDFISELFDK MKAEIRGLDY DARMADLWRA SITENFVTAV
       61 HYLDRDTPQS LVEAPAAALA YARAAAQRDI PLSGLVRAHR LGHARFLEVA MQYVSLLEPA
      121 DRVSTIIELV NRSARLVDLV ADQLIVAYEH EHDRWLSRRS GLQQQWVSEL LADTPVDVPR
      181 AERALGYRLD GVHIAAVVWV DSAVPIGDVV AQFDQVRCLL AGELGPELGP VANSLMVPTD
      241 EREARLWFSP APTRAFAPSR IRAAFESAGI RARLACGRVG DGLRGFRASL KQAERVKALA
      301 LAGGARPGGR VMFYDDVAPV ALLADDLEEL RRFVTDVLGD LSVDDERNSW LRETLREFLL
      361 RNRSYVATAD AMILHRNTIQ YRVIQAMELC GQNLDDPDAA FRVQMALEVC RWMAPAVLRA
      421 KQ
//