LOCUS SIU00043.1 274 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PUTATIVE METHYLTRANSFERASE protein. ACCESSION LT708304-1456 PROTEIN_ID SIU00043.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB1440C" /note="Mb1440c, -, len: 274 aa. Equivalent to Rv1405c, len: 274 aa, from Mycobacterium tuberculosis strain H37Rv, (100% identity in 274 aa overlap). Putative methyltransferase (EC 2.1.1.-), most similar to PMTA_RHOSH|Q05197 phosphatidylethanolamine m-methyltransferase (203 aa), FASTA scores: opt: 219, E(): 2.6e-07, (29.9% identity in 144 aa overlap); similar to Rv1403c|MTCY21B4.20c (59.3% identity in 273 aa overlap), Rv1523, Rv2952, etc. Protein product from Mb1440c detected using shotgun mass spectrometry and SWATH mass spectrometry." /db_xref="GOA:P64842" /db_xref="InterPro:IPR013216" /db_xref="InterPro:IPR029063" /db_xref="UniProtKB/Swiss-Prot:P64842" BEGIN 1 MTIDTPARED QTLAATHRAM WALGDYALMA EEVMAPLGPI LVAAAGIGPG VRVLDVAAGS 61 GNISLPAAKT GATVISTDLT PELLQRSQAR AAQQGLTLQY QEANAQALPF ADDEFDTVIS 121 AIGVMFAPDH QAAADELVRV CRPGGTIGVI SWTCEGFFGR MLATIRPYRP SVSADLPPSA 181 LWGREAYVTG LLGDGVTGLK TARGLLEVKR FDTAQAVHDY FKNNYGPTIE AYAHIGDNAV 241 LAAELDRQLV ELAAQYLSDG VMEWEYLLLT AEKR //