LOCUS       SIU00043.1               274 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PUTATIVE
            METHYLTRANSFERASE protein.
ACCESSION   LT708304-1456
PROTEIN_ID  SIU00043.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1440C"
                     /note="Mb1440c, -, len: 274 aa. Equivalent to Rv1405c,
                     len: 274 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 274 aa overlap). Putative
                     methyltransferase (EC 2.1.1.-), most similar to
                     PMTA_RHOSH|Q05197 phosphatidylethanolamine
                     m-methyltransferase (203 aa), FASTA scores: opt: 219, E():
                     2.6e-07, (29.9% identity in 144 aa overlap); similar to
                     Rv1403c|MTCY21B4.20c (59.3% identity in 273 aa overlap),
                     Rv1523, Rv2952, etc. Protein product from Mb1440c detected
                     using shotgun mass spectrometry and SWATH mass
                     spectrometry."
                     /db_xref="GOA:P64842"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="UniProtKB/Swiss-Prot:P64842"
BEGIN
        1 MTIDTPARED QTLAATHRAM WALGDYALMA EEVMAPLGPI LVAAAGIGPG VRVLDVAAGS
       61 GNISLPAAKT GATVISTDLT PELLQRSQAR AAQQGLTLQY QEANAQALPF ADDEFDTVIS
      121 AIGVMFAPDH QAAADELVRV CRPGGTIGVI SWTCEGFFGR MLATIRPYRP SVSADLPPSA
      181 LWGREAYVTG LLGDGVTGLK TARGLLEVKR FDTAQAVHDY FKNNYGPTIE AYAHIGDNAV
      241 LAAELDRQLV ELAAQYLSDG VMEWEYLLLT AEKR
//