LOCUS       SIT99984.1               386 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 acyl-
            coa dehydrogenase mbtn protein.
ACCESSION   LT708304-1396
PROTEIN_ID  SIT99984.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="mbtn"
                     /locus_tag="BQ2027_MB1381"
                     /note="Mb1381, fadE14, len: 386 aa. Equivalent to Rv1346,
                     len: 386 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 386 aa overlap). Possible fadE14,
                     acyl-CoA dehydrogenase (EC 1.3.99.-), similar to many e.g.
                     NP_251579.1|NC_002516 probable acyl-CoA dehydrogenase from
                     Pseudomonas aeruginosa (386 aa);
                     NP_036951.1|NM_012819|ACDL_RAT|P15650 acyl Coenzyme A
                     dehydrogenase (long chain) from Rattus norvegicus (430
                     aa), FASTA scores: opt: 414, E(): 1.2e-18, (26.1% identity
                     in 376 aa overlap); etc. Protein product from Mb1381
                     detected using SWATH mass spectrometry. Mb1381 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P63432"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR009075"
                     /db_xref="InterPro:IPR009100"
                     /db_xref="InterPro:IPR013786"
                     /db_xref="InterPro:IPR036250"
                     /db_xref="InterPro:IPR037069"
                     /db_xref="UniProtKB/Swiss-Prot:P63432"
BEGIN
        1 MTAGSDLDDF RGLLAKAFDE RVVAWTAEAE AQERFPRQLI EHLGVCGVFD AKWATDARPD
       61 VGKLVELAFA LGQLASAGIG VGVSLHDSAI AILRRFGKSD YLRDICDQAI RGAAVLCIGA
      121 SEESGGSDLQ IVETEIRSRD GGFEVRGVKK FVSLSPIADH IMVVARSVDH DPTSRHGNVA
      181 VVAVPAAQVS VQTPYRKVGA GPLDTAAVCI DTWVPADALV ARAGTGLAAI SWGLAHERMS
      241 IAGQIAASCQ RAIGITLARM MSRRQFGQTL FEHQALRLRM ADLQARVDLL RYALHGIAEQ
      301 GRLELRTAAA VKVTAARLGE EVISECMHIF GGAGYLVDET TLGKWWRDMK LARVGGGTDE
      361 VLWELVAAGM TPDHDGYAAV VGASKA
//